EXP14_ARATH
ID EXP14_ARATH Reviewed; 255 AA.
AC Q9FMA0; Q0WLD1; Q8L9W7;
DT 05-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Expansin-A14;
DE Short=AtEXPA14;
DE AltName: Full=Alpha-expansin-14;
DE Short=At-EXP14;
DE Short=AtEx14;
DE AltName: Full=Ath-ExpAlpha-1.5;
DE Flags: Precursor;
GN Name=EXPA14; Synonyms=EXP14; OrderedLocusNames=At5g56320; ORFNames=MCD7.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT features of the regions of 1,456,315 bp covered by nineteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:41-54(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7-255.
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NOMENCLATURE.
RX PubMed=15604683; DOI=10.1007/s11103-004-0158-6;
RA Kende H., Bradford K.J., Brummell D.A., Cho H.-T., Cosgrove D.J.,
RA Fleming A.J., Gehring C., Lee Y., McQueen-Mason S.J., Rose J.K.C.,
RA Voesenek L.A.C.;
RT "Nomenclature for members of the expansin superfamily of genes and
RT proteins.";
RL Plant Mol. Biol. 55:311-314(2004).
RN [6]
RP FUNCTION.
RX PubMed=22974309; DOI=10.1111/tpj.12013;
RA Lee H.W., Kim M.J., Kim N.Y., Lee S.H., Kim J.;
RT "LBD18 acts as a transcriptional activator that directly binds to the
RT EXPANSIN14 promoter in promoting lateral root emergence of Arabidopsis.";
RL Plant J. 73:212-224(2013).
RN [7]
RP DEVELOPMENTAL STAGE, AND INDUCTION BY AUXIN.
RX PubMed=23872272; DOI=10.1093/pcp/pct105;
RA Lee H.W., Kim J.;
RT "EXPANSINA17 up-regulated by LBD18/ASL20 promotes lateral root formation
RT during the auxin response.";
RL Plant Cell Physiol. 54:1600-1611(2013).
CC -!- FUNCTION: Causes loosening and extension of plant cell walls by
CC disrupting non-covalent bonding between cellulose microfibrils and
CC matrix glucans. No enzymatic activity has been found (By similarity).
CC Target of the transcriptional activator LBD18. Regulated by LBD18 to
CC promote lateral root formation (PubMed:22974309).
CC {ECO:0000250|UniProtKB:Q9LDR9, ECO:0000269|PubMed:22974309}.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall. Membrane; Peripheral
CC membrane protein.
CC -!- DEVELOPMENTAL STAGE: Expressed during lateral root development.
CC {ECO:0000269|PubMed:23872272}.
CC -!- INDUCTION: By auxin. {ECO:0000269|PubMed:23872272}.
CC -!- SIMILARITY: Belongs to the expansin family. Expansin A subfamily.
CC {ECO:0000305}.
CC -!- WEB RESOURCE: Name=EXPANSIN homepage;
CC URL="http://homes.bio.psu.edu/expansins/";
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DR EMBL; AB009049; BAB11259.1; -; Genomic_DNA.
DR EMBL; CP002688; AED96748.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM71008.1; -; Genomic_DNA.
DR EMBL; AK230274; BAF02076.1; -; mRNA.
DR EMBL; AY088179; AAM65722.1; -; mRNA.
DR RefSeq; NP_001332569.1; NM_001345194.1.
DR RefSeq; NP_200443.1; NM_125015.2.
DR AlphaFoldDB; Q9FMA0; -.
DR SMR; Q9FMA0; -.
DR STRING; 3702.AT5G56320.1; -.
DR PaxDb; Q9FMA0; -.
DR PRIDE; Q9FMA0; -.
DR ProteomicsDB; 222306; -.
DR EnsemblPlants; AT5G56320.1; AT5G56320.1; AT5G56320.
DR EnsemblPlants; AT5G56320.2; AT5G56320.2; AT5G56320.
DR GeneID; 835731; -.
DR Gramene; AT5G56320.1; AT5G56320.1; AT5G56320.
DR Gramene; AT5G56320.2; AT5G56320.2; AT5G56320.
DR KEGG; ath:AT5G56320; -.
DR Araport; AT5G56320; -.
DR TAIR; locus:2161028; AT5G56320.
DR eggNOG; ENOG502QPUJ; Eukaryota.
DR HOGENOM; CLU_027462_0_1_1; -.
DR InParanoid; Q9FMA0; -.
DR OMA; FEIRCTG; -.
DR PhylomeDB; Q9FMA0; -.
DR PRO; PR:Q9FMA0; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FMA0; baseline and differential.
DR Genevisible; Q9FMA0; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0010311; P:lateral root formation; IMP:UniProtKB.
DR GO; GO:0009828; P:plant-type cell wall loosening; TAS:UniProtKB.
DR Gene3D; 2.40.40.10; -; 1.
DR Gene3D; 2.60.40.760; -; 1.
DR InterPro; IPR007118; Expan_Lol_pI.
DR InterPro; IPR002963; Expansin.
DR InterPro; IPR007112; Expansin/allergen_DPBB_dom.
DR InterPro; IPR007117; Expansin_CBD.
DR InterPro; IPR036749; Expansin_CBD_sf.
DR InterPro; IPR009009; RlpA-like_DPBB.
DR InterPro; IPR036908; RlpA-like_sf.
DR PANTHER; PTHR31867; PTHR31867; 1.
DR Pfam; PF03330; DPBB_1; 1.
DR Pfam; PF01357; Expansin_C; 1.
DR PRINTS; PR01226; EXPANSIN.
DR PRINTS; PR01225; EXPANSNFAMLY.
DR SMART; SM00837; DPBB_1; 1.
DR SUPFAM; SSF49590; SSF49590; 1.
DR SUPFAM; SSF50685; SSF50685; 1.
DR PROSITE; PS50843; EXPANSIN_CBD; 1.
DR PROSITE; PS50842; EXPANSIN_EG45; 1.
PE 2: Evidence at transcript level;
KW Cell wall; Cell wall biogenesis/degradation; Membrane; Reference proteome;
KW Secreted; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..255
FT /note="Expansin-A14"
FT /id="PRO_0000008695"
FT DOMAIN 47..159
FT /note="Expansin-like EG45"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
FT DOMAIN 169..248
FT /note="Expansin-like CBD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00078"
FT CONFLICT 14
FT /note="M -> I (in Ref. 4; AAM65722)"
FT /evidence="ECO:0000305"
FT CONFLICT 88
FT /note="D -> N (in Ref. 4; AAM65722)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 255 AA; 27733 MW; 22A7DD423381CB4E CRC64;
MEFFGKMIIS LSLMMMIMWK SVDGYSSGWV NARATFYGGA DASGTMGGAC GYGNLYSQGY
GTNTAALSTA LFNGGQSCGA CFQIKCVDDP KWCIGGTITV TGTNFCPPNF AQANNAGGWC
NPPQHHFDLA QPIFLRIAQY KAGVVPVQYR RVACRRKGGI RFTINGHSYF NLVLITNVAG
AGDVISVSIK GTNTRWQSMS RNWGQNWQSN AKLDGQALSF KVTTSDGRTV ISNNATPRNW
SFGQTYTGKQ FRAQR
