EXP17_ARATH
ID EXP17_ARATH Reviewed; 255 AA.
AC Q9ZSI1;
DT 05-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=Putative expansin-A17;
DE Short=AtEXPA17;
DE AltName: Full=Alpha-expansin-17;
DE Short=At-EXP17;
DE Short=AtEx17;
DE AltName: Full=Ath-ExpAlpha-1.13;
DE Flags: Precursor;
GN Name=EXPA17; Synonyms=EXP17; OrderedLocusNames=At4g01630;
GN ORFNames=T15B16.16;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NOMENCLATURE.
RX PubMed=15604683; DOI=10.1007/s11103-004-0158-6;
RA Kende H., Bradford K.J., Brummell D.A., Cho H.-T., Cosgrove D.J.,
RA Fleming A.J., Gehring C., Lee Y., McQueen-Mason S.J., Rose J.K.C.,
RA Voesenek L.A.C.;
RT "Nomenclature for members of the expansin superfamily of genes and
RT proteins.";
RL Plant Mol. Biol. 55:311-314(2004).
RN [4]
RP FUNCTION, DEVELOPMENTAL STAGE, AND INDUCTION BY AUXIN.
RX PubMed=23872272; DOI=10.1093/pcp/pct105;
RA Lee H.W., Kim J.;
RT "EXPANSINA17 up-regulated by LBD18/ASL20 promotes lateral root formation
RT during the auxin response.";
RL Plant Cell Physiol. 54:1600-1611(2013).
CC -!- FUNCTION: Causes loosening and extension of plant cell walls by
CC disrupting non-covalent bonding between cellulose microfibrils and
CC matrix glucans. No enzymatic activity has been found (By similarity).
CC Target of the transcriptional activator LBD18. Regulated by LBD18 to
CC promote lateral root formation (PubMed:23872272).
CC {ECO:0000250|UniProtKB:Q9LDR9, ECO:0000269|PubMed:23872272}.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall. Membrane; Peripheral
CC membrane protein.
CC -!- DEVELOPMENTAL STAGE: Expressed during lateral root development.
CC {ECO:0000269|PubMed:23872272}.
CC -!- INDUCTION: By auxin. {ECO:0000269|PubMed:23872272}.
CC -!- MISCELLANEOUS: Plants silencing EXPA17 exhibit reduced number of
CC emerged lateral roots. Plants over-expressing EXPA17 show increased
CC density of emerged lateral roots. {ECO:0000269|PubMed:23872272}.
CC -!- SIMILARITY: Belongs to the expansin family. Expansin A subfamily.
CC {ECO:0000305}.
CC -!- WEB RESOURCE: Name=EXPANSIN homepage;
CC URL="http://homes.bio.psu.edu/expansins/";
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DR EMBL; AF104919; AAC72858.1; -; Genomic_DNA.
DR EMBL; AL161492; CAB77733.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE82054.1; -; Genomic_DNA.
DR PIR; T02010; T02010.
DR RefSeq; NP_192072.1; NM_116393.2.
DR AlphaFoldDB; Q9ZSI1; -.
DR SMR; Q9ZSI1; -.
DR STRING; 3702.AT4G01630.1; -.
DR PaxDb; Q9ZSI1; -.
DR PRIDE; Q9ZSI1; -.
DR ProteomicsDB; 222416; -.
DR EnsemblPlants; AT4G01630.1; AT4G01630.1; AT4G01630.
DR GeneID; 827983; -.
DR Gramene; AT4G01630.1; AT4G01630.1; AT4G01630.
DR KEGG; ath:AT4G01630; -.
DR Araport; AT4G01630; -.
DR TAIR; locus:2133427; AT4G01630.
DR eggNOG; ENOG502QS90; Eukaryota.
DR HOGENOM; CLU_027462_0_1_1; -.
DR InParanoid; Q9ZSI1; -.
DR OMA; MNGRNYF; -.
DR OrthoDB; 1084583at2759; -.
DR PhylomeDB; Q9ZSI1; -.
DR PRO; PR:Q9ZSI1; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9ZSI1; baseline and differential.
DR Genevisible; Q9ZSI1; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0010311; P:lateral root formation; IMP:UniProtKB.
DR GO; GO:0009828; P:plant-type cell wall loosening; TAS:UniProtKB.
DR Gene3D; 2.40.40.10; -; 1.
DR Gene3D; 2.60.40.760; -; 1.
DR InterPro; IPR007118; Expan_Lol_pI.
DR InterPro; IPR002963; Expansin.
DR InterPro; IPR007112; Expansin/allergen_DPBB_dom.
DR InterPro; IPR007117; Expansin_CBD.
DR InterPro; IPR036749; Expansin_CBD_sf.
DR InterPro; IPR009009; RlpA-like_DPBB.
DR InterPro; IPR036908; RlpA-like_sf.
DR PANTHER; PTHR31867; PTHR31867; 1.
DR Pfam; PF03330; DPBB_1; 1.
DR Pfam; PF01357; Expansin_C; 1.
DR PRINTS; PR01226; EXPANSIN.
DR PRINTS; PR01225; EXPANSNFAMLY.
DR SMART; SM00837; DPBB_1; 1.
DR SUPFAM; SSF49590; SSF49590; 1.
DR SUPFAM; SSF50685; SSF50685; 1.
DR PROSITE; PS50843; EXPANSIN_CBD; 1.
DR PROSITE; PS50842; EXPANSIN_EG45; 1.
PE 2: Evidence at transcript level;
KW Cell wall; Cell wall biogenesis/degradation; Membrane; Reference proteome;
KW Secreted; Signal.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..255
FT /note="Putative expansin-A17"
FT /id="PRO_0000008698"
FT DOMAIN 46..161
FT /note="Expansin-like EG45"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
FT DOMAIN 171..251
FT /note="Expansin-like CBD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00078"
SQ SEQUENCE 255 AA; 27715 MW; A33A62D3522A530F CRC64;
MTKIFSLLVA MIFSTMFFMK ISSVSAGWLQ AHATFYGGSD ASGTMGGACG YGNLYTDGYK
TNTAALSTAL FNDGKSCGGC YQILCDATKV PQWCLKGKSI TITATNFCPP NFAQASDNGG
WCNPPRPHFD MAQPAFLTIA KYKAGIVPIL YKKVGCRRSG GMRFTINGRN YFELVLISNV
AGGGEISKVW IKGSKSNKWE TMSRNWGANY QSNTYLNGQS LSFKVQLSDG SIKAALNVVP
SNWRFGQSFK SNVNF
