EXPA2_ARATH
ID EXPA2_ARATH Reviewed; 255 AA.
AC Q38866; Q9FLC5;
DT 05-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2006, sequence version 2.
DT 03-AUG-2022, entry version 146.
DE RecName: Full=Expansin-A2;
DE Short=AtEXPA2;
DE AltName: Full=Alpha-expansin-2;
DE Short=At-EXP2;
DE Short=AtEx2;
DE AltName: Full=Ath-ExpAlpha-1.12;
DE Flags: Precursor;
GN Name=EXPA2; Synonyms=EXP2; OrderedLocusNames=At5g05290; ORFNames=K18I23.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=7568110; DOI=10.1073/pnas.92.20.9245;
RA Shcherban T.Y., Shi J., Durachko D.M., Guiltinan M.J., McQueen-Mason S.J.,
RA Shieh M., Cosgrove D.J.;
RT "Molecular cloning and sequence analysis of expansins - a highly conserved,
RT multigene family of proteins that mediate cell wall extension in plants.";
RL Proc. Natl. Acad. Sci. U.S.A. 92:9245-9249(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9679202; DOI=10.1093/dnares/5.2.131;
RA Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence
RT features of the regions of 1,381,565 bp covered by twenty one physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:131-145(1998).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NOMENCLATURE.
RX PubMed=15604683; DOI=10.1007/s11103-004-0158-6;
RA Kende H., Bradford K.J., Brummell D.A., Cho H.-T., Cosgrove D.J.,
RA Fleming A.J., Gehring C., Lee Y., McQueen-Mason S.J., Rose J.K.C.,
RA Voesenek L.A.C.;
RT "Nomenclature for members of the expansin superfamily of genes and
RT proteins.";
RL Plant Mol. Biol. 55:311-314(2004).
CC -!- FUNCTION: Causes loosening and extension of plant cell walls by
CC disrupting non-covalent bonding between cellulose microfibrils and
CC matrix glucans. No enzymatic activity has been found (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall. Membrane; Peripheral
CC membrane protein.
CC -!- SIMILARITY: Belongs to the expansin family. Expansin A subfamily.
CC {ECO:0000305}.
CC -!- WEB RESOURCE: Name=EXPANSIN homepage;
CC URL="http://homes.bio.psu.edu/expansins/";
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DR EMBL; U30481; AAB38073.1; -; mRNA.
DR EMBL; AB010692; BAB09972.1; -; Genomic_DNA.
DR EMBL; CP002688; AED90852.1; -; Genomic_DNA.
DR PIR; T50656; T50656.
DR RefSeq; NP_196148.1; NM_120611.3.
DR AlphaFoldDB; Q38866; -.
DR SMR; Q38866; -.
DR STRING; 3702.AT5G05290.1; -.
DR PaxDb; Q38866; -.
DR PRIDE; Q38866; -.
DR ProteomicsDB; 222305; -.
DR EnsemblPlants; AT5G05290.1; AT5G05290.1; AT5G05290.
DR GeneID; 830411; -.
DR Gramene; AT5G05290.1; AT5G05290.1; AT5G05290.
DR KEGG; ath:AT5G05290; -.
DR Araport; AT5G05290; -.
DR TAIR; locus:2153569; AT5G05290.
DR eggNOG; ENOG502QPUJ; Eukaryota.
DR HOGENOM; CLU_027462_0_1_1; -.
DR InParanoid; Q38866; -.
DR OMA; CEDDPEW; -.
DR OrthoDB; 1114831at2759; -.
DR PhylomeDB; Q38866; -.
DR PRO; PR:Q38866; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q38866; baseline and differential.
DR Genevisible; Q38866; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0009664; P:plant-type cell wall organization; IEA:InterPro.
DR Gene3D; 2.40.40.10; -; 1.
DR Gene3D; 2.60.40.760; -; 1.
DR InterPro; IPR007118; Expan_Lol_pI.
DR InterPro; IPR002963; Expansin.
DR InterPro; IPR007112; Expansin/allergen_DPBB_dom.
DR InterPro; IPR007117; Expansin_CBD.
DR InterPro; IPR036749; Expansin_CBD_sf.
DR InterPro; IPR009009; RlpA-like_DPBB.
DR InterPro; IPR036908; RlpA-like_sf.
DR PANTHER; PTHR31867; PTHR31867; 1.
DR Pfam; PF03330; DPBB_1; 1.
DR Pfam; PF01357; Expansin_C; 1.
DR PRINTS; PR01226; EXPANSIN.
DR PRINTS; PR01225; EXPANSNFAMLY.
DR SMART; SM00837; DPBB_1; 1.
DR SUPFAM; SSF49590; SSF49590; 1.
DR SUPFAM; SSF50685; SSF50685; 1.
DR PROSITE; PS50843; EXPANSIN_CBD; 1.
DR PROSITE; PS50842; EXPANSIN_EG45; 1.
PE 2: Evidence at transcript level;
KW Cell wall; Cell wall biogenesis/degradation; Disulfide bond; Membrane;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..255
FT /note="Expansin-A2"
FT /id="PRO_0000008683"
FT DOMAIN 50..162
FT /note="Expansin-like EG45"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
FT DOMAIN 172..252
FT /note="Expansin-like CBD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00078"
FT DISULFID 53..81
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
FT DISULFID 84..157
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
FT DISULFID 89..96
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
FT CONFLICT 88
FT /note="Q -> T (in Ref. 1; AAB38073)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 255 AA; 27749 MW; 53E678633B2C4152 CRC64;
MNLTEYSHIL FLSLCTLNFC LYSINSDDNG GWERGHATFY GGADASGTMG GACGYGNLHS
QGYGLQTAAL STALFNSGQK CGACFELQCE DDPEWCIPGS IIVSATNFCP PNFALANDNG
GWCNPPLKHF DLAEPAFLQI AQYRAGIVPV AFRRVPCEKG GGIRFTINGN PYFDLVLITN
VGGAGDIRAV SLKGSKTDQW QSMSRNWGQN WQSNTYLRGQ SLSFQVTDSD GRTVVSYDVV
PHDWQFGQTF EGGQF
