EXPA3_ARATH
ID EXPA3_ARATH Reviewed; 262 AA.
AC O80932;
DT 05-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 142.
DE RecName: Full=Expansin-A3;
DE Short=AtEXPA3;
DE AltName: Full=Alpha-expansin-3;
DE Short=At-EXP3;
DE Short=AtEx3;
DE AltName: Full=Ath-ExpAlpha-1.9;
DE Flags: Precursor;
GN Name=EXPA3; Synonyms=EXP3; OrderedLocusNames=At2g37640; ORFNames=F13M22.14;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NOMENCLATURE.
RX PubMed=15604683; DOI=10.1007/s11103-004-0158-6;
RA Kende H., Bradford K.J., Brummell D.A., Cho H.-T., Cosgrove D.J.,
RA Fleming A.J., Gehring C., Lee Y., McQueen-Mason S.J., Rose J.K.C.,
RA Voesenek L.A.C.;
RT "Nomenclature for members of the expansin superfamily of genes and
RT proteins.";
RL Plant Mol. Biol. 55:311-314(2004).
CC -!- FUNCTION: Causes loosening and extension of plant cell walls by
CC disrupting non-covalent bonding between cellulose microfibrils and
CC matrix glucans. No enzymatic activity has been found (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall. Membrane; Peripheral
CC membrane protein.
CC -!- SIMILARITY: Belongs to the expansin family. Expansin A subfamily.
CC {ECO:0000305}.
CC -!- WEB RESOURCE: Name=EXPANSIN homepage;
CC URL="http://homes.bio.psu.edu/expansins/";
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DR EMBL; AC004684; AAC23634.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09429.1; -; Genomic_DNA.
DR EMBL; AY090368; AAL91271.1; -; mRNA.
DR EMBL; AY122898; AAM67431.1; -; mRNA.
DR PIR; T02530; T02530.
DR RefSeq; NP_181300.1; NM_129320.4.
DR AlphaFoldDB; O80932; -.
DR SMR; O80932; -.
DR STRING; 3702.AT2G37640.1; -.
DR PaxDb; O80932; -.
DR ProteomicsDB; 222238; -.
DR EnsemblPlants; AT2G37640.1; AT2G37640.1; AT2G37640.
DR GeneID; 818341; -.
DR Gramene; AT2G37640.1; AT2G37640.1; AT2G37640.
DR KEGG; ath:AT2G37640; -.
DR Araport; AT2G37640; -.
DR TAIR; locus:2040686; AT2G37640.
DR eggNOG; ENOG502SI5V; Eukaryota.
DR HOGENOM; CLU_027462_0_1_1; -.
DR InParanoid; O80932; -.
DR OMA; IRIMMAR; -.
DR OrthoDB; 979254at2759; -.
DR PhylomeDB; O80932; -.
DR PRO; PR:O80932; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O80932; baseline and differential.
DR Genevisible; O80932; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009664; P:plant-type cell wall organization; IEA:InterPro.
DR GO; GO:0009739; P:response to gibberellin; TAS:TAIR.
DR GO; GO:0010114; P:response to red light; IEP:TAIR.
DR GO; GO:0006949; P:syncytium formation; IEP:TAIR.
DR Gene3D; 2.40.40.10; -; 1.
DR Gene3D; 2.60.40.760; -; 1.
DR InterPro; IPR007118; Expan_Lol_pI.
DR InterPro; IPR002963; Expansin.
DR InterPro; IPR007112; Expansin/allergen_DPBB_dom.
DR InterPro; IPR007117; Expansin_CBD.
DR InterPro; IPR036749; Expansin_CBD_sf.
DR InterPro; IPR009009; RlpA-like_DPBB.
DR InterPro; IPR036908; RlpA-like_sf.
DR PANTHER; PTHR31867; PTHR31867; 1.
DR Pfam; PF03330; DPBB_1; 1.
DR Pfam; PF01357; Expansin_C; 1.
DR PRINTS; PR01226; EXPANSIN.
DR PRINTS; PR01225; EXPANSNFAMLY.
DR SMART; SM00837; DPBB_1; 1.
DR SUPFAM; SSF49590; SSF49590; 1.
DR SUPFAM; SSF50685; SSF50685; 1.
DR PROSITE; PS50843; EXPANSIN_CBD; 1.
DR PROSITE; PS50842; EXPANSIN_EG45; 1.
PE 2: Evidence at transcript level;
KW Cell wall; Cell wall biogenesis/degradation; Disulfide bond; Membrane;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..25
FT /evidence="ECO:0000255"
FT CHAIN 26..262
FT /note="Expansin-A3"
FT /id="PRO_0000008684"
FT DOMAIN 54..168
FT /note="Expansin-like EG45"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
FT DOMAIN 178..257
FT /note="Expansin-like CBD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00078"
FT DISULFID 57..85
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
FT DISULFID 88..163
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
FT DISULFID 93..100
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
SQ SEQUENCE 262 AA; 28266 MW; AFC4D0EC599B4882 CRC64;
MTATAFRVGL WLAVTASFLL TATNAKIPGV YSGGPWQNAH ATFYGGSDAS GTMGGACGYG
NLYSQGYGVN TAALSTALFN NGFSCGACFE IKCTDDPRWC VPGNPSILVT ATNFCPPNFA
QPSDDGGWCN PPREHFDLAM PMFLKIGLYR AGIVPVSYRR VPCRKIGGIR FTVNGFRYFN
LVLVTNVAGA GDINGVSVKG SKTDWVRMSR NWGQNWQSNA VLIGQSLSFR VTASDRRSST
SWNVAPATWQ FGQTFSGKNF RV
