EXPA8_ARATH
ID EXPA8_ARATH Reviewed; 253 AA.
AC O22874;
DT 05-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 144.
DE RecName: Full=Expansin-A8;
DE Short=AtEXPA8;
DE AltName: Full=Alpha-expansin-8;
DE Short=At-EXP8;
DE Short=AtEx8;
DE AltName: Full=Ath-ExpAlpha-1.11;
DE Flags: Precursor;
GN Name=EXPA8; Synonyms=EXP8; OrderedLocusNames=At2g40610; ORFNames=T2P4.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NOMENCLATURE.
RX PubMed=15604683; DOI=10.1007/s11103-004-0158-6;
RA Kende H., Bradford K.J., Brummell D.A., Cho H.-T., Cosgrove D.J.,
RA Fleming A.J., Gehring C., Lee Y., McQueen-Mason S.J., Rose J.K.C.,
RA Voesenek L.A.C.;
RT "Nomenclature for members of the expansin superfamily of genes and
RT proteins.";
RL Plant Mol. Biol. 55:311-314(2004).
CC -!- FUNCTION: Causes loosening and extension of plant cell walls by
CC disrupting non-covalent bonding between cellulose microfibrils and
CC matrix glucans. No enzymatic activity has been found (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall. Membrane; Peripheral
CC membrane protein.
CC -!- SIMILARITY: Belongs to the expansin family. Expansin A subfamily.
CC {ECO:0000305}.
CC -!- WEB RESOURCE: Name=EXPANSIN homepage;
CC URL="http://homes.bio.psu.edu/expansins/";
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DR EMBL; AC002336; AAB87577.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09854.1; -; Genomic_DNA.
DR EMBL; AY086770; AAM63821.1; -; mRNA.
DR PIR; F84831; F84831.
DR RefSeq; NP_181593.1; NM_129623.3.
DR AlphaFoldDB; O22874; -.
DR SMR; O22874; -.
DR STRING; 3702.AT2G40610.1; -.
DR PaxDb; O22874; -.
DR PRIDE; O22874; -.
DR ProteomicsDB; 221818; -.
DR EnsemblPlants; AT2G40610.1; AT2G40610.1; AT2G40610.
DR GeneID; 818656; -.
DR Gramene; AT2G40610.1; AT2G40610.1; AT2G40610.
DR KEGG; ath:AT2G40610; -.
DR Araport; AT2G40610; -.
DR TAIR; locus:2061918; AT2G40610.
DR eggNOG; ENOG502QPUJ; Eukaryota.
DR HOGENOM; CLU_027462_0_1_1; -.
DR InParanoid; O22874; -.
DR OMA; CFWWIAG; -.
DR OrthoDB; 1114831at2759; -.
DR PhylomeDB; O22874; -.
DR PRO; PR:O22874; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O22874; baseline and differential.
DR Genevisible; O22874; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009664; P:plant-type cell wall organization; IEA:InterPro.
DR GO; GO:0009635; P:response to herbicide; IEP:TAIR.
DR GO; GO:0006949; P:syncytium formation; IEP:TAIR.
DR Gene3D; 2.40.40.10; -; 1.
DR Gene3D; 2.60.40.760; -; 1.
DR InterPro; IPR007118; Expan_Lol_pI.
DR InterPro; IPR002963; Expansin.
DR InterPro; IPR007112; Expansin/allergen_DPBB_dom.
DR InterPro; IPR007117; Expansin_CBD.
DR InterPro; IPR036749; Expansin_CBD_sf.
DR InterPro; IPR009009; RlpA-like_DPBB.
DR InterPro; IPR036908; RlpA-like_sf.
DR PANTHER; PTHR31867; PTHR31867; 1.
DR Pfam; PF03330; DPBB_1; 1.
DR Pfam; PF01357; Expansin_C; 1.
DR PRINTS; PR01226; EXPANSIN.
DR PRINTS; PR01225; EXPANSNFAMLY.
DR SMART; SM00837; DPBB_1; 1.
DR SUPFAM; SSF49590; SSF49590; 1.
DR SUPFAM; SSF50685; SSF50685; 1.
DR PROSITE; PS50843; EXPANSIN_CBD; 1.
DR PROSITE; PS50842; EXPANSIN_EG45; 1.
PE 2: Evidence at transcript level;
KW Cell wall; Cell wall biogenesis/degradation; Disulfide bond; Membrane;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..25
FT /evidence="ECO:0000255"
FT CHAIN 26..253
FT /note="Expansin-A8"
FT /id="PRO_0000008689"
FT DOMAIN 48..160
FT /note="Expansin-like EG45"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
FT DOMAIN 170..250
FT /note="Expansin-like CBD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00078"
FT DISULFID 51..79
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
FT DISULFID 82..155
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
FT DISULFID 87..94
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
SQ SEQUENCE 253 AA; 27260 MW; 08C42880D523DD8A CRC64;
MYTPSYLKYS IISIISVLFL QGTHGDDGGW QGGHATFYGG EDASGTMGGA CGYGNLYGQG
YGTNTAALST ALFNNGLTCG ACYEMKCNDD PRWCLGSTIT VTATNFCPPN PGLSNDNGGW
CNPPLQHFDL AEPAFLQIAQ YRAGIVPVSF RRVPCMKKGG IRFTINGHSY FNLVLISNVG
GAGDVHAVSI KGSKTQSWQA MSRNWGQNWQ SNSYMNDQSL SFQVTTSDGR TLVSNDVAPS
NWQFGQTYQG GQF
