EXPL5_DICDI
ID EXPL5_DICDI Reviewed; 238 AA.
AC Q86AV4; Q550V5;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Expansin-like protein 5;
DE Short=Ddexpl5;
DE Flags: Precursor;
GN Name=expl5; ORFNames=DDB_G0276937;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [3]
RP SUBCELLULAR LOCATION, DEVELOPMENTAL STAGE, AND FUNCTION.
RX PubMed=12832080; DOI=10.1016/s0014-5793(03)00598-2;
RA Darley C.P., Li Y., Schaap P., McQueen-Mason S.J.;
RT "Expression of a family of expansin-like proteins during the development of
RT Dictyostelium discoideum.";
RL FEBS Lett. 546:416-418(2003).
RN [4]
RP FUNCTION.
RX PubMed=11891242; DOI=10.1104/pp.010658;
RA Li Y., Darley C.P., Ongaro V., Fleming A., Schipper O., Baldauf S.L.,
RA McQueen-Mason S.J.;
RT "Plant expansins are a complex multigene family with an ancient
RT evolutionary origin.";
RL Plant Physiol. 128:854-864(2002).
CC -!- FUNCTION: May serve to lubricate the movement of the cellulose
CC microfibrils during cell growth and wall extension and/or may serve to
CC maintain the fluid state of the slug cell wall.
CC {ECO:0000269|PubMed:11891242, ECO:0000269|PubMed:12832080}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:12832080}.
CC -!- DEVELOPMENTAL STAGE: No detectable expression.
CC {ECO:0000269|PubMed:12832080}.
CC -!- SIMILARITY: Belongs to the expansin family. Expansin A subfamily.
CC {ECO:0000305}.
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DR EMBL; AAFI02000019; EAL68970.1; -; Genomic_DNA.
DR RefSeq; XP_642827.1; XM_637735.1.
DR AlphaFoldDB; Q86AV4; -.
DR SMR; Q86AV4; -.
DR CAZy; CBM63; Carbohydrate-Binding Module Family 63.
DR PaxDb; Q86AV4; -.
DR EnsemblProtists; EAL68970; EAL68970; DDB_G0276937.
DR GeneID; 8620690; -.
DR KEGG; ddi:DDB_G0276937; -.
DR dictyBase; DDB_G0276937; expl5.
DR eggNOG; ENOG502S9SU; Eukaryota.
DR HOGENOM; CLU_071727_0_0_1; -.
DR InParanoid; Q86AV4; -.
DR OMA; HFFSYAY; -.
DR PhylomeDB; Q86AV4; -.
DR PRO; PR:Q86AV4; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR Gene3D; 2.40.40.10; -; 1.
DR Gene3D; 2.60.40.760; -; 1.
DR InterPro; IPR007112; Expansin/allergen_DPBB_dom.
DR InterPro; IPR036749; Expansin_CBD_sf.
DR InterPro; IPR009009; RlpA-like_DPBB.
DR InterPro; IPR036908; RlpA-like_sf.
DR Pfam; PF03330; DPBB_1; 1.
DR SMART; SM00837; DPBB_1; 1.
DR SUPFAM; SSF49590; SSF49590; 1.
DR SUPFAM; SSF50685; SSF50685; 1.
DR PROSITE; PS50842; EXPANSIN_EG45; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Glycoprotein; Reference proteome; Secreted; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..238
FT /note="Expansin-like protein 5"
FT /id="PRO_0000368218"
FT DOMAIN 45..145
FT /note="Expansin-like EG45"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
FT CARBOHYD 89
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 48..78
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
FT DISULFID 81..140
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
SQ SEQUENCE 238 AA; 25544 MW; 57511A955F6667D0 CRC64;
MRINFKLILI ILTSFYGIIN CQSTCPYSKT VINGASATFY SAMDNGNCGF GKLTGPTGPG
NYMIAALGTK LYQNGAQCGQ CFKISNSKNA SVTVMATDSC NDAGYCQRDN HFDLSPTAFS
ILGAQSQGVL DGLSYVKVPC RVSGNVKVML KDGSNAYWTS FLVFNNAIDV KQVSIKLSGS
STYVPLTQTT YNYWPSSITA GSFQVRIESI GGEFIYVTIP SVVSSKIYDT GSQFSSSC
