ID   EXPR_PECPM              Reviewed;         245 AA.
AC   Q47189; K4FNI9;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Transcriptional activator protein ExpR;
GN   Name=expR; OrderedLocusNames=W5S_4606;
OS   Pectobacterium parmentieri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=1905730;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=SCC3193;
RA   Heikinheimo R., Mae A., Flego D., Pirhonen M., Koiv V., Palva E.T.;
RL   Submitted (DEC-1994) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCC3193;
RX   PubMed=23045508; DOI=10.1128/jb.00681-12;
RA   Koskinen J.P., Laine P., Niemi O., Nykyri J., Harjunpaa H., Auvinen P.,
RA   Paulin L., Pirhonen M., Palva T., Holm L.;
RT   "Genome sequence of Pectobacterium sp. strain SCC3193.";
RL   J. Bacteriol. 194:6004-6004(2012).
CC   -!- FUNCTION: Functions as an OHLL responsive transcriptional regulator
CC       that acts in virulence (soft rot disease) through the activation of
CC       genes for plant tissue macerating enzymes.
CC   -!- SIMILARITY: Belongs to the autoinducer-regulated transcriptional
CC       regulatory protein family. {ECO:0000305}.
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DR   EMBL; X80475; CAA56646.1; -; Genomic_DNA.
DR   EMBL; CP003415; AFI92652.1; -; Genomic_DNA.
DR   PIR; S49900; S49900.
DR   RefSeq; WP_014702024.1; NZ_QESW01000003.1.
DR   AlphaFoldDB; Q47189; -.
DR   SMR; Q47189; -.
DR   STRING; 1905730.W5S_4606; -.
DR   PRIDE; Q47189; -.
DR   EnsemblBacteria; AFI92652; AFI92652; W5S_4606.
DR   KEGG; pec:W5S_4606; -.
DR   PATRIC; fig|1166016.3.peg.4668; -.
DR   eggNOG; COG2771; Bacteria.
DR   HOGENOM; CLU_072786_5_0_6; -.
DR   OMA; RESLQWV; -.
DR   OrthoDB; 1687028at2; -.
DR   Proteomes; UP000008044; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009372; P:quorum sensing; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.450.80; -; 1.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR005143; TF_LuxR_autoind-bd_dom.
DR   InterPro; IPR036693; TF_LuxR_autoind-bd_dom_sf.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF03472; Autoind_bind; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF75516; SSF75516; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Quorum sensing; Transcription;
KW   Transcription regulation; Virulence.
FT   CHAIN           1..245
FT                   /note="Transcriptional activator protein ExpR"
FT                   /id="PRO_0000184152"
FT   DOMAIN          173..238
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   DNA_BIND        197..216
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
SQ   SEQUENCE   245 AA;  28540 MW;  75A58F073D08E9DF CRC64;
     MSQLFYNNET ISRIIKSQFD MALSHYGDIK YAYMVLNKKK PTEILIISNH HDEWREIYQA
     NNYQHIDPVV IAALNKITPF PWDEDLLVST QLKMSKIFNL SREHNITNGY TFVLHDHSNN
     LVMLSIMIDE SNVSNIDDVI ESNKDKLQMT LMTIHAETIS LYREMIRNKE DERSNDKDIF
     SQRENEILYW ASMGKTYQEI ALILDIKTGT VKFHIGNVVK KLGVLNAKHA IRLGIELQLI
     RPVQS