EXRN_BPT3
ID EXRN_BPT3 Reviewed; 302 AA.
AC P20321;
DT 01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1991, sequence version 1.
DT 02-DEC-2020, entry version 66.
DE RecName: Full=Exodeoxyribonuclease;
DE Short=Exonuclease;
DE EC=3.1.11.3;
GN Name=6;
OS Enterobacteria phage T3 (Bacteriophage T3).
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Caudovirales; Autographiviridae; Studiervirinae; Teetrevirus;
OC Escherichia virus T3.
OX NCBI_TaxID=10759;
OH NCBI_TaxID=562; Escherichia coli.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Luria;
RX PubMed=2614843; DOI=10.1016/0022-2836(89)90102-2;
RA Beck P.J., Gonzalez S., Ward C.L., Molineux I.J.;
RT "Sequence of bacteriophage T3 DNA from gene 2.5 through gene 9.";
RL J. Mol. Biol. 210:687-701(1989).
CC -!- FUNCTION: This enzyme is essential for phage DNA replication; it is
CC believed to function in the removal of DNA-linked RNA primers. It is
CC also necessary for host DNA degradation and phage genetic
CC recombination.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage in the 5'- to 3'-direction to yield
CC nucleoside 5'-phosphates.; EC=3.1.11.3;
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X17255; CAA35147.1; -; Genomic_DNA.
DR PIR; S07503; S07503.
DR RefSeq; NP_523327.1; NC_003298.1.
DR GeneID; 927425; -.
DR KEGG; vg:927425; -.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR SUPFAM; SSF88723; SSF88723; 1.
PE 4: Predicted;
KW Exonuclease; Hydrolase; Nuclease.
FT CHAIN 1..302
FT /note="Exodeoxyribonuclease"
FT /id="PRO_0000106504"
SQ SEQUENCE 302 AA; 34627 MW; D89C9CE2CC5D4773 CRC64;
MALLDLKQFY ELREGCDDKG ILVMDGDWLV FQAMSAAEFD ASWEEEIWHR CCDHAKARQI
LEDSIKSYET RKKAWVGAPI VLAFTDSVNW RKELVDPNYK ANRKATKKPV GYFEFLEALF
EREEFYCIRE PMLEGDDVMG VIASNPSAFG ARKAVIISCD KDFKTIPNCD FLWCTTGNIL
TQTKETADWW HLFQTIKGDM TDGYSGIPGW GDTAEGFLND PFIVEPVESV LKSGKNKGQT
VTKWVKRAPD ATETLWDCIK SIGAKAGMTE QEIIKQGQMA RILRFEEYNY IDKEIYLWTP
RS