ID   EXTN_TOBAC              Reviewed;         620 AA.
AC   P13983;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Extensin;
DE   AltName: Full=Cell wall hydroxyproline-rich glycoprotein;
DE   Flags: Precursor;
GN   Name=HRGPNT3;
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND TISSUE SPECIFICITY.
RC   STRAIN=cv. Xanthi; TISSUE=Leaf;
RX   PubMed=2612909; DOI=10.1101/gad.3.10.1639;
RA   Keller B., Lamb C.J.;
RT   "Specific expression of a novel cell wall hydroxyproline-rich glycoprotein
RT   gene in lateral root initiation.";
RL   Genes Dev. 3:1639-1646(1989).
CC   -!- FUNCTION: Has a specialized structural function, possibly in the
CC       mechanical penetration of the cortex and epidermis of the main root.
CC   -!- SUBCELLULAR LOCATION: Secreted, primary cell wall.
CC   -!- TISSUE SPECIFICITY: Expressed in the tip of the emerging lateral roots.
CC       {ECO:0000269|PubMed:2612909}.
CC   -!- PTM: Hydroxylated on proline residues in the S-P-P-P-P repeat.
CC   -!- PTM: O-glycosylated on hydroxyprolines.
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DR   EMBL; X13885; CAA32090.1; -; Genomic_DNA.
DR   PIR; S06733; S06733.
DR   AlphaFoldDB; P13983; -.
DR   STRING; 4097.P13983; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0009530; C:primary cell wall; IEA:UniProtKB-SubCell.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Cell wall; Cell wall biogenesis/degradation; Glycoprotein; Hydroxylation;
KW   Reference proteome; Repeat; Secreted; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..620
FT                   /note="Extensin"
FT                   /id="PRO_0000008731"
FT   REPEAT          70..73
FT                   /note="H-A-P-P"
FT   REPEAT          148..151
FT                   /note="H-A-P-P"
FT   REPEAT          229..235
FT                   /note="1"
FT   REPEAT          236..242
FT                   /note="2"
FT   REGION          34..620
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          205..620
FT                   /note="Contains the Ser-Pro(4) repeats"
FT   REGION          229..242
FT                   /note="2 X 7 AA tandem repeats of T-H-R-H-A-P-P"
FT   REGION          499..600
FT                   /note="3 X approximate tandem repeats"
FT   COMPBIAS        36..132
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        174..231
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        239..620
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   620 AA;  65407 MW;  641DD2278AB28524 CRC64;
     MKLSTLFALV LLLQSTAILS LVAAEATTQY GGYLPPPVTS QPPPSSIGLS PPSAPTTTPP
     SRGHVPSPRH APPRHAYPPP SHGHLPPSVG GPPPHRGHLP PSRGFNPPPS PVISPSHPPP
     SYGAPPPSHG PGHLPSHGQR PPSPSHGHAP PSGGHTPPRG QHPPSHRRPS PPSRHGHPPP
     PTYAQPPPTP IYSPSPQVQP PPTYSPPPPT HVQPTPSPPS RGHQPQPPTH RHAPPTHRHA
     PPTHQPSPLR HLPPSPRRQP QPPTYSPPPP AYAQSPQPSP TYSPPPPTYS PPPPSPIYSP
     PPPAYSPSPP PTPTPTFSPP PPAYSPPPTY SPPPPTYLPL PSSPIYSPPP PVYSPPPPPS
     YSPPPPTYLP PPPPSSPPPP SFSPPPPTYE QSPPPPPAYS PPLPAPPTYS PPPPTYSPPP
     PTYAQPPPLP PTYSPPPPAY SPPPPPTYSP PPPTYSPPPP AYAQPPPPPP TYSPPPPAYS
     PPPPSPIYSP PPPQVQPLPP TFSPPPPRRI HLPPPPHRQP RPPTPTYGQP PSPPTFSPPP
     PRQIHSPPPP HWQPRTPTPT YGQPPSPPTF SAPPPRQIHS PPPPHRQPRP PTPTYGQPPS
     PPTTYSPPSP PPYGLLLSTP