ID   EXUR_DICCH              Reviewed;         259 AA.
AC   Q9X9E0;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Exu regulon transcriptional regulator;
GN   Name=exuR {ECO:0000303|PubMed:9530868};
OS   Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Dickeya.
OX   NCBI_TaxID=556;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=EC16;
RX   PubMed=9530868; DOI=10.1094/MPMI.1998.11.4.270;
RA   Haseloff B.J., Freeman T.L., Valmeekam V., Melkus M.W., Oner F.,
RA   Valachovic M.S., San Francisco M.J.;
RT   "The exuT gene of Erwinia chrysanthemi EC16: nucleotide sequence,
RT   expression, localization, and relevance of the gene product.";
RL   Mol. Plant Microbe Interact. 11:270-276(1998).
RN   [2]
RP   FUNCTION, AND DISRUPTION PHENOTYPE.
RX   PubMed=11386378; DOI=10.1094/mpmi.2001.14.6.816;
RA   Valmeekam V., Loh Y.L., San Francisco M.J.;
RT   "Control of exuT activity for galacturonate transport by the negative
RT   regulator ExuR in Erwinia chrysanthemi EC16.";
RL   Mol. Plant Microbe Interact. 14:816-820(2001).
CC   -!- FUNCTION: Major regulator of exuT transcription.
CC       {ECO:0000269|PubMed:11386378}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- DISRUPTION PHENOTYPE: Mutant shows constitutively high galacturonate
CC       uptake activity under inducing and non-inducing conditions.
CC       {ECO:0000269|PubMed:11386378}.
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DR   EMBL; U86689; AAD30185.1; -; Genomic_DNA.
DR   RefSeq; WP_015847841.1; NZ_JSYH01000014.1.
DR   AlphaFoldDB; Q9X9E0; -.
DR   SMR; Q9X9E0; -.
DR   OMA; TWQEHRK; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.20.120.530; -; 1.
DR   InterPro; IPR011711; GntR_C.
DR   InterPro; IPR008920; TF_FadR/GntR_C.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF07729; FCD; 1.
DR   Pfam; PF00392; GntR; 1.
DR   PRINTS; PR00035; HTHGNTR.
DR   SMART; SM00895; FCD; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF48008; SSF48008; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   4: Predicted;
KW   Cytoplasm; DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..259
FT                   /note="Exu regulon transcriptional regulator"
FT                   /id="PRO_0000050625"
FT   DOMAIN          7..75
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
FT   DNA_BIND        35..54
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
SQ   SEQUENCE   259 AA;  30115 MW;  FA4B23DFC6884052 CRC64;
     MALTESRRLY QQLAAELKQR IENGVYPVGD KLPAERNISE EMNVSRTVVR EAIIMLEVEG
     YVEVRKGSGI HVISNQQRHL LAANGSDADF LTAGPFELLQ ARQLIESNIA EFAATQVTRQ
     DIIQLMEIQE NARQEDRFRD SEWDLKFHVQ VALATQNSAM ATIVEKMWSQ RIHNPYWRKL
     HEHIDDKSIE SWCEDHDQIL KALIRKDPYA AKLAMWQHLE NTKQMLFRAT TDDFEFNVDR
     YMFAENPVVH LDHITNGKL