ID   F10A5_HUMAN             Reviewed;         369 AA.
AC   Q8NFI4;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 124.
DE   RecName: Full=Putative protein FAM10A5;
DE   AltName: Full=Suppression of tumorigenicity 13 pseudogene 5;
GN   Name=ST13P5; Synonyms=FAM10A5;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=12079276; DOI=10.1006/geno.2002.6792;
RA   Sossey-Alaoui K., Kitamura E., Head K., Cowell J.K.;
RT   "Characterization of FAM10A4, a member of the ST13 tumor suppressor gene
RT   family that maps to the 13q14.3 region associated with B-Cell leukemia,
RT   multiple myeloma, and prostate cancer.";
RL   Genomics 80:5-7(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FAM10 family. {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR   EMBL; AF512499; AAM44055.1; -; mRNA.
DR   EMBL; AC107948; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; Q8NFI4; -.
DR   SMR; Q8NFI4; -.
DR   IntAct; Q8NFI4; 1.
DR   GlyConnect; 2066; 1 N-Linked glycan (1 site).
DR   GlyGen; Q8NFI4; 1 site, 2 N-linked glycans (1 site).
DR   iPTMnet; Q8NFI4; -.
DR   SwissPalm; Q8NFI4; -.
DR   BioMuta; HGNC:18556; -.
DR   DMDM; 74762570; -.
DR   EPD; Q8NFI4; -.
DR   jPOST; Q8NFI4; -.
DR   MassIVE; Q8NFI4; -.
DR   MaxQB; Q8NFI4; -.
DR   PeptideAtlas; Q8NFI4; -.
DR   PRIDE; Q8NFI4; -.
DR   ProteomicsDB; 73315; -.
DR   GeneCards; ST13P5; -.
DR   HGNC; HGNC:18556; ST13P5.
DR   neXtProt; NX_Q8NFI4; -.
DR   InParanoid; Q8NFI4; -.
DR   PhylomeDB; Q8NFI4; -.
DR   PathwayCommons; Q8NFI4; -.
DR   Pharos; Q8NFI4; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q8NFI4; protein.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd14438; Hip_N; 1.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR034649; Hip_N.
DR   InterPro; IPR041243; STI1.
DR   InterPro; IPR006636; STI1_HS-bd.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   Pfam; PF18253; HipN; 1.
DR   Pfam; PF17830; STI1; 1.
DR   SMART; SM00727; STI1; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   PROSITE; PS50005; TPR; 3.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   5: Uncertain;
KW   Acetylation; Cytoplasm; Phosphoprotein; Reference proteome; Repeat;
KW   TPR repeat.
FT   CHAIN           1..369
FT                   /note="Putative protein FAM10A5"
FT                   /id="PRO_0000190817"
FT   REPEAT          114..147
FT                   /note="TPR 1"
FT   REPEAT          149..181
FT                   /note="TPR 2"
FT   REPEAT          183..215
FT                   /note="TPR 3"
FT   DOMAIN          319..358
FT                   /note="STI1"
FT   REGION          38..98
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          256..300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        50..71
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        256..274
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         346
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P50502"
FT   MOD_RES         353
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:Q99L47"
FT   MOD_RES         360
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:Q99L47"
SQ   SEQUENCE   369 AA;  41378 MW;  9BAD620C24E2D137 CRC64;
     MDPCKVNELR AFVKMCKQDP SVLHTEEMRF LREWVESMGG KVPPATQKAK SEENTKEEKP
     DSKKVEEDLK ADEPSTEESD LEIDKEGVIE PDTDAPQEMG DENVEITEEM MDQANDKKVA
     AIEVLNDGEL QKAIDLFTDA IKLNPRLAIL YAKRASVFVK LQKPNAAIQD CDRAIEINPD
     SAQPYKWRGK AHRLLGHWEE AAHDLAFACK LDYDEDASAM LKEVQPRAQK IAEHWRKYER
     KHEEREIKER IERVKKAQEE QERAQREEEA RRQSGAHYGP FPGGFPGGMP GNFPGGMPGM
     GGDMPGMAGM PGLNEILSDP EALAAMQDPE VMVAFQDVAQ NPANMSKYQS NPKVMNLISK
     LSAKFGGQA