ID   F110D_MOUSE             Reviewed;         271 AA.
AC   Q80X91;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 2.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Protein FAM110D;
GN   Name=Fam110d {ECO:0000312|MGI:MGI:1919940};
GN   Synonyms=Grrp1 {ECO:0000312|MGI:MGI:1919940};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the FAM110 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL627314; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC048704; AAH48704.2; -; mRNA.
DR   CCDS; CCDS38913.1; -.
DR   RefSeq; NP_001092766.1; NM_001099296.2.
DR   RefSeq; XP_006539261.1; XM_006539198.2.
DR   RefSeq; XP_006539262.1; XM_006539199.3.
DR   RefSeq; XP_006539263.1; XM_006539200.2.
DR   AlphaFoldDB; Q80X91; -.
DR   STRING; 10090.ENSMUSP00000060143; -.
DR   iPTMnet; Q80X91; -.
DR   PhosphoSitePlus; Q80X91; -.
DR   PaxDb; Q80X91; -.
DR   PRIDE; Q80X91; -.
DR   ProteomicsDB; 275563; -.
DR   Antibodypedia; 2884; 76 antibodies from 15 providers.
DR   Ensembl; ENSMUST00000060050; ENSMUSP00000060143; ENSMUSG00000050105.
DR   GeneID; 72690; -.
DR   KEGG; mmu:72690; -.
DR   UCSC; uc008veo.1; mouse.
DR   CTD; 79927; -.
DR   MGI; MGI:1919940; Fam110d.
DR   VEuPathDB; HostDB:ENSMUSG00000050105; -.
DR   eggNOG; ENOG502S0DB; Eukaryota.
DR   GeneTree; ENSGT00950000183056; -.
DR   HOGENOM; CLU_050540_1_0_1; -.
DR   InParanoid; Q80X91; -.
DR   OMA; KWLYGCQ; -.
DR   OrthoDB; 745936at2759; -.
DR   PhylomeDB; Q80X91; -.
DR   TreeFam; TF330964; -.
DR   BioGRID-ORCS; 72690; 1 hit in 73 CRISPR screens.
DR   ChiTaRS; Grrp1; mouse.
DR   PRO; PR:Q80X91; -.
DR   Proteomes; UP000000589; Chromosome 4.
DR   RNAct; Q80X91; protein.
DR   Bgee; ENSMUSG00000050105; Expressed in brain blood vessel and 146 other tissues.
DR   Genevisible; Q80X91; MM.
DR   InterPro; IPR025740; FAM110.
DR   InterPro; IPR025741; FAM110_C.
DR   InterPro; IPR025739; FAM110_N.
DR   PANTHER; PTHR14758; PTHR14758; 1.
DR   Pfam; PF14160; FAM110_C; 1.
DR   Pfam; PF14161; FAM110_N; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..271
FT                   /note="Protein FAM110D"
FT                   /id="PRO_0000318717"
FT   REGION          1..84
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          118..149
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          186..242
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        17..34
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        201..216
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   271 AA;  28712 MW;  0A961BEA09BBF1A5 CRC64;
     MLLSSPTTPS RGRTPSAVER LEADKAKYVK THQVIVRRQE PALRGGPGPL TPHPCNELGA
     SASPRTPGPA RRGSGRRQPR PDSLIFYRQK RDCKASVNKE NAKGQGLVRR LFLGATRDAA
     PSSPAPTERP GAPAGWAGSP DTPEATGKRA VCPTCSLPLS EKERFFNYCG LERALVEVLG
     AERFSPQSWG AEHGPQVATS PPPGSGDTSD WTSSDRDAGS PDCAGGGGGS EAAGSARDGR
     PTVSVVERNA RVIQWLYGCQ RARAPPRESE V