ID   F118B_BOVIN             Reviewed;         351 AA.
AC   Q5E977;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Protein FAM118B;
GN   Name=FAM118B;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal cerebellum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in Cajal bodies formation.
CC       {ECO:0000250|UniProtKB:Q9BPY3}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, Cajal body
CC       {ECO:0000250|UniProtKB:Q9BPY3}.
CC   -!- SIMILARITY: Belongs to the FAM118 family. {ECO:0000305}.
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DR   EMBL; BT021043; AAX09060.1; -; mRNA.
DR   EMBL; BC118445; AAI18446.1; -; mRNA.
DR   RefSeq; NP_001015677.1; NM_001015677.2.
DR   AlphaFoldDB; Q5E977; -.
DR   SMR; Q5E977; -.
DR   STRING; 9913.ENSBTAP00000016141; -.
DR   PaxDb; Q5E977; -.
DR   PRIDE; Q5E977; -.
DR   Ensembl; ENSBTAT00000016141; ENSBTAP00000016141; ENSBTAG00000012169.
DR   GeneID; 540626; -.
DR   KEGG; bta:540626; -.
DR   CTD; 79607; -.
DR   VEuPathDB; HostDB:ENSBTAG00000012169; -.
DR   VGNC; VGNC:108123; FAM118B.
DR   eggNOG; ENOG502QSNY; Eukaryota.
DR   GeneTree; ENSGT00390000010215; -.
DR   HOGENOM; CLU_1291510_0_0_1; -.
DR   InParanoid; Q5E977; -.
DR   OMA; WGKQNEL; -.
DR   OrthoDB; 752035at2759; -.
DR   Proteomes; UP000009136; Chromosome 29.
DR   Bgee; ENSBTAG00000012169; Expressed in oocyte and 106 other tissues.
DR   GO; GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0030576; P:Cajal body organization; IEA:InterPro.
DR   InterPro; IPR038916; FAM118.
DR   InterPro; IPR033352; FAM118B.
DR   InterPro; IPR039444; SIR2-like.
DR   PANTHER; PTHR28623; PTHR28623; 1.
DR   PANTHER; PTHR28623:SF1; PTHR28623:SF1; 1.
DR   Pfam; PF13289; SIR2_2; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Nucleus; Phosphoprotein; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BPY3"
FT   CHAIN           2..351
FT                   /note="Protein FAM118B"
FT                   /id="PRO_0000295102"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BPY3"
FT   MOD_RES         9
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BPY3"
SQ   SEQUENCE   351 AA;  39537 MW;  4112F2DCC74EC6A6 CRC64;
     MASTGSQASD IDKILGFFSD GAPPTKKPRK LLPSLKTKKP RELVLVIGTG ISAAVAPQVP
     ALKSWKGLIQ ALLDAAIDFD LLEDEESKKF QKCLHEDKNL VHVAHDLIQK LSPRTSNVRS
     TFFKDCLYEV FDDLESKMED SGKQLLQSVL HLMENGALVL TTNFDNLLEL YAADQGKQLE
     SLDLTDEKKV LEWAQEKRKL SVLHIHGVYT NPSGIVLHPA GYQNVLRNTE VMREIQKLYE
     NKSFLFLGCG WTVDDTTFQA LFLEAVKHKS DLEHFMLVRR GDVDEFKKLR ENMLDKGIKV
     ISYGNDYADL PEYFKRLTCE ISTRGRSAGI VREGQLNGSS TAHSEIRDHS T