ID   F118B_RAT               Reviewed;         350 AA.
AC   Q4QQT2;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Protein FAM118B;
GN   Name=Fam118b;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May play a role in Cajal bodies formation.
CC       {ECO:0000250|UniProtKB:Q9BPY3}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, Cajal body
CC       {ECO:0000250|UniProtKB:Q9BPY3}.
CC   -!- SIMILARITY: Belongs to the FAM118 family. {ECO:0000305}.
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DR   EMBL; BC098017; AAH98017.1; -; mRNA.
DR   RefSeq; NP_001020454.1; NM_001025283.1.
DR   RefSeq; XP_006242846.1; XM_006242784.3.
DR   RefSeq; XP_008764278.1; XM_008766056.2.
DR   AlphaFoldDB; Q4QQT2; -.
DR   SMR; Q4QQT2; -.
DR   STRING; 10116.ENSRNOP00000015366; -.
DR   jPOST; Q4QQT2; -.
DR   PaxDb; Q4QQT2; -.
DR   PRIDE; Q4QQT2; -.
DR   Ensembl; ENSRNOT00000015366; ENSRNOP00000015366; ENSRNOG00000011543.
DR   GeneID; 315549; -.
DR   KEGG; rno:315549; -.
DR   UCSC; RGD:1307173; rat.
DR   CTD; 79607; -.
DR   RGD; 1307173; Fam118b.
DR   eggNOG; ENOG502QSNY; Eukaryota.
DR   GeneTree; ENSGT00390000010215; -.
DR   HOGENOM; CLU_063072_0_0_1; -.
DR   InParanoid; Q4QQT2; -.
DR   OMA; WGKQNEL; -.
DR   OrthoDB; 752035at2759; -.
DR   PhylomeDB; Q4QQT2; -.
DR   PRO; PR:Q4QQT2; -.
DR   Proteomes; UP000002494; Chromosome 8.
DR   Bgee; ENSRNOG00000011543; Expressed in duodenum and 19 other tissues.
DR   Genevisible; Q4QQT2; RN.
DR   GO; GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.
DR   GO; GO:0042802; F:identical protein binding; ISO:RGD.
DR   GO; GO:0030576; P:Cajal body organization; IEA:InterPro.
DR   InterPro; IPR038916; FAM118.
DR   InterPro; IPR033352; FAM118B.
DR   InterPro; IPR039444; SIR2-like.
DR   PANTHER; PTHR28623; PTHR28623; 1.
DR   PANTHER; PTHR28623:SF1; PTHR28623:SF1; 1.
DR   Pfam; PF13289; SIR2_2; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Nucleus; Phosphoprotein; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BPY3"
FT   CHAIN           2..350
FT                   /note="Protein FAM118B"
FT                   /id="PRO_0000295106"
FT   REGION          330..350
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BPY3"
FT   MOD_RES         9
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BPY3"
SQ   SEQUENCE   350 AA;  39423 MW;  385902877E00655D CRC64;
     MASTGSQASD IDKIFGFFND GEPPTKKPRK LLPSLKTKKP RELVLVIGTG ISAAVAPQVP
     ALKSWKGLIQ ALLDAAIDFD LLEDEESKKF QKCLHEDKNL VHVAHDLIQK LSPRTSNVRS
     TFFKDCLYEV FDDLESKMED SGKQLLQSVL HLMENGALVL TTNFDNLLEL YAADQGKQLE
     SLDLTDEKKV LEWAQEKRKL SVLHIHGVYT NPSGIVLHPA GYQNVLRNTE VMREIQKLYE
     NKSFLFLGCG WTVDDTTFQA LFLEAVKHKS DLEHFMLVRR GDVDEFKKLR ENMLDKGIKV
     ISYGNDYADL PEYFKRLTCE ISTRGRSGMA REGQLNGSSA AHGEIRGCST