ID   F11_VACCP               Reviewed;         337 AA.
AC   P29888;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   12-AUG-2020, entry version 37.
DE   RecName: Full=Protein F11;
DE   AltName: Full=Protein F7;
GN   ORFNames=F7;
OS   Vaccinia virus (strain L-IVP) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=31531;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Mikryukov N.N., Chizhikov V.E., Prikhod'Ko G.G., Urmmanov I.M.,
RA   Serpinskii O.I., Blinov V.M., Nikulin A.E., Vasilenko S.K.;
RT   "Structural-functional organization of segment of vaccinia virus genome.";
RL   Biotekhnologiya 4:442-449(1988).
CC   -!- FUNCTION: Stimulates increases in peripheral microtubule dynamics and
CC       may increase the motility of the infected cells, contributing to cell-
CC       to-cell spread of the virus. Seems to inhibit the signaling via the
CC       GTPase RHOA and DIAPH1/mDia (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the poxviridae F11 protein family.
CC       {ECO:0000305}.
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DR   EMBL; M57977; AAA48287.1; -; Genomic_DNA.
DR   InterPro; IPR007027; Poxvirus_F11.
DR   Pfam; PF04943; Pox_F11; 1.
DR   PIRSF; PIRSF015981; VAC_F11L; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..337
FT                   /note="Protein F11"
FT                   /id="PRO_0000099499"
SQ   SEQUENCE   337 AA;  37757 MW;  A4D33CA399869FAC CRC64;
     MGFCIPSRSK MLKRGSRKSS SILARRPTPK KMNIVTDLEN RLKKNSYIEN TNQGNILMDS
     IFVSTMPVET LFGSYITDDY ELKDLLNVTY NIKPDIVPDI KLDAVLDRDG NFRPADCFLV
     KLKHRDGFTK GALYLGHSAG FTATICLKNE GVSGLYIPGA SVIRSNICQG DTVSRSSRGV
     QFLPQIGGEA IFLIVSLCPT KKLVETGFVI PEISSNDNAK IAARILSEKR KDTIAHIDTL
     IQHRQQLELA YYNSCMLTEF LHYCNSYAGT IKESLLKETI QKDINITHTN ITTLLNETAK
     VIKLVKSLVD KEDTDIVNNF ITKEIKTVEV LKQRQNS