ID   F120A_XENTR             Reviewed;        1043 AA.
AC   Q6DEZ2;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Constitutive coactivator of PPAR-gamma-like protein 1 homolog;
DE   AltName: Full=Protein FAM120A;
GN   Name=fam120a;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May bee involved in the oxidative stress-induced survival
CC       signaling. Binds RNA. May participate in mRNA transport in the
CC       cytoplasm (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cell membrane
CC       {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic
CC       side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the constitutive coactivator of PPAR-gamma
CC       family. {ECO:0000305}.
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DR   EMBL; BC076951; AAH76951.1; -; mRNA.
DR   RefSeq; NP_001005059.1; NM_001005059.1.
DR   AlphaFoldDB; Q6DEZ2; -.
DR   STRING; 8364.ENSXETP00000048821; -.
DR   GeneID; 448612; -.
DR   KEGG; xtr:448612; -.
DR   CTD; 23196; -.
DR   Xenbase; XB-GENE-5767697; fam120a.
DR   eggNOG; ENOG502QQNQ; Eukaryota.
DR   InParanoid; Q6DEZ2; -.
DR   OrthoDB; 203269at2759; -.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR026784; Coact_PPARg.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   PANTHER; PTHR15976; PTHR15976; 2.
DR   SUPFAM; SSF88723; SSF88723; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Cytoplasm; Membrane; Reference proteome; RNA-binding.
FT   CHAIN           1..1043
FT                   /note="Constitutive coactivator of PPAR-gamma-like protein
FT                   1 homolog"
FT                   /id="PRO_0000363781"
FT   REGION          353..497
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          801..1043
FT                   /note="RNA binding"
FT                   /evidence="ECO:0000250"
FT   REGION          929..1043
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        364..393
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        404..448
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        450..470
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        471..489
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        962..976
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        983..1022
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1024..1043
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1043 AA;  115375 MW;  365DC00C6DF4D02C CRC64;
     MGVQGFQEYM EKHCPSAVVP VELQKLARGS LVGGGRQRPP QSPLRLLVDA ENCLHRLYGG
     FYTDWVSGGQ WNHMLGYLGA LAKACYAGNI QLFVFFNGAL EKGRLHEWVK RQGNERQTAQ
     QIVSHIQNKG TPPPKVWFLP PICMAHCIRL ALLRFHIKVA QSIEDHHQEV ITFCRENGFH
     GLVAYDSDYA LCNIPYYFSA HALKLSRNGK SLTTSQYLMH EVAKQLDLNP NRFPIFAALL
     GNHILPDEDL AAFHWSLLGP EHPLASLKVR AHQLVLPPCD VVIKAVADYV RNIQDTNDLD
     AIAKDVFQHS QSRTDDKVSR FKKAIAYYRA TNKPLSCPPA HYLGRPNPGG IHSMVPPYPS
     PQMLNIPQGS VQSRPMTGGK CVSEQNNYSN IPHEGKHTPL YERSSPINPA QSGSPNHVDS
     NYFPPSSASS SSENEDGNGG SANHVSGNKP TWDKGKKSEK ANKKDSTEQA KAEVPSPSGS
     GNKGTDKKAN QPGHMQIPCL LSMPTRNHMD ITTPPLPQVA PEVLRVAEHR HKKGLMYPYI
     FHVLTKGEMK IPVTIEDEIN KDLPPAAILY RPVRQYVYGV LFSLAESRKK AERLAFRKNR
     MPPEFYVPDY PVIIKEWAAY KGKSPQTPEL VEALAFREWT CPNLKKLWLG KAVEDKNRRM
     RAFLACMRSD TPAMLNPANV PTHLMVLCCV LRYMVQWPGI RILRRQELDA FLAQAISPKL
     YEPDQLQELK IDNLDPRGIQ LSALFMSGVD MAFLANDACG QPIPWEHCCP WMYFDGKLLQ
     AKLNKATREK ASLIDLCDGQ VELATKVEKM RQSILEGLHF SRQNHPLPFP PPPAMPFYPA
     AMYPRPCGPM PPPQGRGRGF PGVQPMPSQG GKLEIAGTVV GQWAGTRRGR GRGPFPLQVV
     SVGGANRGRP RGVISTPIIR TFGRGGRYYG RGFKNQGPPQ AKPPYATSAE EVAKELKTQS
     EDSKSSAVSS DGSLAENGLA SEEAPASQMN GGSGEARASS NSESALSSDS KLCNTNPHLN
     ALNADSVRHK EQPLEGAVAN KEE