ID   F120B_BOVIN             Reviewed;         700 AA.
AC   A6QNT4;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Constitutive coactivator of peroxisome proliferator-activated receptor gamma;
DE            Short=Constitutive coactivator of PPAR-gamma;
DE            Short=Constitutive coactivator of PPARG;
DE   AltName: Full=Protein FAM120B;
GN   Name=FAM120B; Synonyms=CCPG;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal skin;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Functions as a transactivator of PPARG and ESR1. Functions in
CC       adipogenesis through PPARG activation (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with ESR1 and RXRA. Interacts with PPARG; in a
CC       ligand-independent manner (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the constitutive coactivator of PPAR-gamma
CC       family. {ECO:0000305}.
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DR   EMBL; BC148988; AAI48989.1; -; mRNA.
DR   RefSeq; NP_001095977.1; NM_001102507.1.
DR   AlphaFoldDB; A6QNT4; -.
DR   SMR; A6QNT4; -.
DR   PaxDb; A6QNT4; -.
DR   PRIDE; A6QNT4; -.
DR   Ensembl; ENSBTAT00000055791; ENSBTAP00000053047; ENSBTAG00000003884.
DR   GeneID; 524306; -.
DR   KEGG; bta:524306; -.
DR   CTD; 84498; -.
DR   VEuPathDB; HostDB:ENSBTAG00000003884; -.
DR   VGNC; VGNC:50072; FAM120B.
DR   eggNOG; ENOG502QRMW; Eukaryota.
DR   GeneTree; ENSGT00530000063168; -.
DR   HOGENOM; CLU_007639_0_0_1; -.
DR   InParanoid; A6QNT4; -.
DR   OrthoDB; 203269at2759; -.
DR   Proteomes; UP000009136; Chromosome 9.
DR   Bgee; ENSBTAG00000003884; Expressed in oocyte and 110 other tissues.
DR   ExpressionAtlas; A6QNT4; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0045444; P:fat cell differentiation; IBA:GO_Central.
DR   GO; GO:0035357; P:peroxisome proliferator activated receptor signaling pathway; IBA:GO_Central.
DR   InterPro; IPR026784; Coact_PPARg.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   PANTHER; PTHR15976; PTHR15976; 1.
DR   SUPFAM; SSF88723; SSF88723; 1.
PE   2: Evidence at transcript level;
KW   Activator; Differentiation; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..700
FT                   /note="Constitutive coactivator of peroxisome proliferator-
FT                   activated receptor gamma"
FT                   /id="PRO_0000332989"
SQ   SEQUENCE   700 AA;  79076 MW;  9C3EBCC324E92370 CRC64;
     MGVRGLHGFV ASSCPHVCTV VNFKELAERH RSQHPGGTPT IVVDAMCCLR YWYTPESWVC
     GGQWREYYSS LREFVRTFTA VGIKLIFFFD GMVEQSKRDE WVKRRLKNNR EIAKIFHYIK
     SRREQPGRNM FFIPSGLAIF TRFALKALGQ ETLCSLQEAD YEVASYGFQN NCLGILGEDT
     DYLIYDTCPY FSISELSLDS LDTVMLCREK LCQSLGLHLA DLPLLACLLG NDVIPEGMFE
     SFRYKCLTSY ASVRESCDRK GNVILAVAEH ISKVLRLHQG EKKLEEMLPL GPNKALFYKG
     VASYLLPGQK SPWFIQKPED VVTLDKQVLS MSSDPESKQE FPVCMDSESK QKLPVGTDPE
     FNLEAPMCTN TEVKQEDPVN VGPEAKHQVT VVLDPEILKV ARAQHVQAES YLVYSVMSSG
     EVECSNSLED ATDQALPSQA FVYRPVRQRV YSLLLGGGGG GSSTGPAVKE WFVYSGNPLR
     QPDLVRPLQM NIPGGTPSLR QLWLSQEPGI QAQRLDTLLA CFDLSSSREE LQAVERPFQA
     LCCLLVYLFV QVDTLCLEDL HAFIAQALCL QGKPTMELAD LQLDHIDPRA VQLATLLVRG
     LTTLVLVNGA CGSPWEMADF MPWHLFDGKL FHQKYLQSEK GYTAEVLVEQ NRSHVTRFHT
     LKSVVCKACG KESRPIVSRR HWRPHHAGSR QYEPDQWRRY