F133_DANRE
ID F133_DANRE Reviewed; 259 AA.
AC A1A5I1; Q1RM45; Q503Y9; Q6DH73;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 18-MAR-2008, sequence version 2.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=Protein FAM133;
GN Name=fam133; ORFNames=si:ch211-287b5.3, zgc:153800;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=WIK; TISSUE=Brain, and Larval eye;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FAM133 family. {ECO:0000305}.
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DR EMBL; BX936336; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CT027751; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC076108; AAH76108.1; -; mRNA.
DR EMBL; BC095122; AAH95122.1; -; mRNA.
DR EMBL; BC115144; AAI15145.1; -; mRNA.
DR EMBL; BC128660; AAI28661.1; -; mRNA.
DR RefSeq; NP_001073556.1; NM_001080087.1.
DR AlphaFoldDB; A1A5I1; -.
DR STRING; 7955.ENSDARP00000083980; -.
DR PaxDb; A1A5I1; -.
DR PRIDE; A1A5I1; -.
DR Ensembl; ENSDART00000089547; ENSDARP00000083980; ENSDARG00000013863.
DR GeneID; 790942; -.
DR KEGG; dre:790942; -.
DR CTD; 257415; -.
DR ZFIN; ZDB-GENE-060503-229; fam133b.
DR eggNOG; ENOG502RXMT; Eukaryota.
DR GeneTree; ENSGT00730000111097; -.
DR HOGENOM; CLU_108741_0_0_1; -.
DR InParanoid; A1A5I1; -.
DR OMA; KEKCIRS; -.
DR OrthoDB; 1561261at2759; -.
DR TreeFam; TF350193; -.
DR PRO; PR:A1A5I1; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 19.
DR Bgee; ENSDARG00000013863; Expressed in somite and 27 other tissues.
DR ExpressionAtlas; A1A5I1; baseline.
DR InterPro; IPR026766; Fam133.
DR PANTHER; PTHR31911; PTHR31911; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..259
FT /note="Protein FAM133"
FT /id="PRO_0000287621"
FT REGION 18..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..101
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..231
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 232..251
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 106
FT /note="E -> K (in Ref. 2; AAI15145)"
FT /evidence="ECO:0000305"
FT CONFLICT 132
FT /note="S -> L (in Ref. 2; AAH95122/AAI28661)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 259 AA; 29831 MW; 5ABF88159B631DD1 CRC64;
MGKRDNRVAY LNPIAAARAR GPAPTSGTTI QDYLSRPRPS WEEVKEQLEK KRKGSRALAD
FEDKMNARWK KELEKNREKV LGGGDKKEKE KEKDKEKEKK EKKKKEKKKS SRHSSSSSSS
SSSSDSSSSS SSDAEDDDEK KNLKKKKKRK RSSTRKASDE TDSESETDSR ESFKKKRKKT
DGEKDKDEKD SRKKRKAERS QSESSDESDV DKDADSKKKK HSSEEKEKIT DKSKKKKKKK
KHKKHSKKKK RKTSSSELD
