ID   F135B_XENLA             Reviewed;        1376 AA.
AC   Q641I1;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=Protein FAM135B;
GN   Name=fam135b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the FAM135 family. {ECO:0000305}.
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DR   EMBL; BC082356; AAH82356.1; -; mRNA.
DR   RefSeq; NP_001087835.1; NM_001094366.1.
DR   AlphaFoldDB; Q641I1; -.
DR   ESTHER; xenla-q641i1; Duf_676.
DR   PRIDE; Q641I1; -.
DR   DNASU; 447696; -.
DR   GeneID; 447696; -.
DR   KEGG; xla:447696; -.
DR   CTD; 447696; -.
DR   Xenbase; XB-GENE-5763437; fam135b.L.
DR   OrthoDB; 1132320at2759; -.
DR   Proteomes; UP000186698; Chromosome 6L.
DR   Bgee; 447696; Expressed in brain.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR022122; DUF3657.
DR   InterPro; IPR007751; DUF676_lipase-like.
DR   InterPro; IPR044294; Lipase-like.
DR   PANTHER; PTHR12482; PTHR12482; 2.
DR   Pfam; PF12394; DUF3657; 1.
DR   Pfam; PF05057; DUF676; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..1376
FT                   /note="Protein FAM135B"
FT                   /id="PRO_0000314173"
FT   REGION          431..489
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        442..489
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1376 AA;  154441 MW;  4947D091F14C77FC CRC64;
     MSEVQGTIEF SIELHKFHNV DLFQRGYYHV RASLKASSRI PHRLVATLVG QTDDPGPYPP
     CVYDNVVYSR MFQILYRNED IDINDVMAFK VHLLLDGERV EDALSEVDFQ LKLDLHFTDS
     EQQLKDMSAV PLISSRTLGL YFHPTSGLHH HVPVMFDYFH LSVISVTVHG SLIALHQPLI
     SFARPVKASW LGKSGQELVT DNTSISMENL VFGSAYCKPP SSEGSYVPSE DCIQHAYKWH
     KDLCQLLLSA YSALGLCHAN VLKEIPDLPH SEIEELPTER TLSQLCNQLQ LLSDPEEITE
     QISKDLAWLR SQLLITWSHF LETVTLQPDV TSYLMQEHHT LRVRRFSEAF FYTEHEKPAV
     LTFQENLIQS QSNLSTEIRN SEYLAALPPL PIECLDIDGD WNSIPIIFED RYVECPRKDY
     ITDNALAEPA NEDECEFSEE SPSENTHVGS KPHSIQSTTV HENASFEKPN VGTKAQEDCS
     TEGPEQGFDH NQEATSVESE FVADFTPLPI PPSETSDSGA KLSLSALNED CDQVTRCYQE
     PKRTPGVTYI KVKPQSQDQY KGETVLIVSS QYGNSLSLAN SEAPQSESET MNSNNGMRTY
     EHIALHEISS TKNELISTLK SQKSRQCSHI LLKSSSTELI RNSTEDTLMV KSCPRDIYEK
     SSLFASGCIK RSSSVISDSG IESEPSSVAW CDVHNRRMDL NSDKDLLLQL SKQHWAYGNS
     LEGDHMESNT SLPSGIQASL ASINSLPFEE EDREMELSKL TKSVSAPQIS SPEETLNDLL
     NNKLVGEIIH SLKKCSSEEK EEESQTAMNY YNNITNDIIS ELANDTHNTN GTKSPESSLA
     NVFIQGLIPN SESGVIDDYI FNDPVVPKAD DFPSVHQETI LCDLNSTDDQ NILDHSNKME
     HVAKACSFSA DPLVDVNSIT HTSFSVIAPA KEIFEDFPVL HEIELSEDSV ESIDQSIDNY
     YHELYSIEKE VSNNRTDGAS ELEETSASLS TVRVLERRKG VELVNLSVSC TATCLPFSSM
     QKDTPVIPGF STKQALFPIT RQPLGSFEVN SSNSNTDEES NERMLSFHQA KDKFRKELKF
     EGFLYSDQPV LASDVPYFPP EEEQTEDGIH LVVCVHGLDG NSADLRLVKT FLELGLPGAN
     LDFLMSEKNQ TDTFADFDAM TDRLIDEIVQ HIQLYNLSIS RISFIGHSLG TIIIRSVLTR
     PRFRYYLNKL HTFLSLSGPH LGTLYSNSTL VNTGLWLMQK LKKSGSLLQL TFRDNADLRK
     CFLYQLSQKP GLQYFKNVVL VASPQDRYVP FHSARIEMCK NATKDRHTGP VYTEMINNLL
     QPVIDSKDCT LIRHNVSHAL PNTANTLIGR AAHIAVLDSE LFLEKFFLVA GLGYFK