F136A_MOUSE
ID F136A_MOUSE Reviewed; 138 AA.
AC Q9CR98; Q91YY1;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Protein FAM136A;
GN Name=Fam136a;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Cerebellum, Embryo, and Small intestine;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Ebert L., Muenstermann E., Schatten R., Henze S., Bohn E., Mollenhauer J.,
RA Wiemann S., Schick M., Korn B.;
RT "Cloning of mouse full open reading frames in Gateway(R) system entry
RT vector (pDONR201).";
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Czech II, FVB/N, and FVB/N-3; TISSUE=Liver, and Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Brown adipose tissue, Kidney, Liver, Lung, and Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SIMILARITY: Belongs to the FAM136 family. {ECO:0000305}.
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DR EMBL; AK005280; BAB23928.1; -; mRNA.
DR EMBL; AK008550; BAB25737.1; -; mRNA.
DR EMBL; AK141279; BAE24632.1; -; mRNA.
DR EMBL; CT010180; CAJ18388.1; -; mRNA.
DR EMBL; BC013621; AAH13621.1; -; mRNA.
DR EMBL; BC024049; AAH24049.1; -; mRNA.
DR EMBL; BC103775; AAI03776.1; -; mRNA.
DR CCDS; CCDS20309.1; -.
DR RefSeq; NP_079867.1; NM_025591.2.
DR AlphaFoldDB; Q9CR98; -.
DR SMR; Q9CR98; -.
DR BioGRID; 211510; 2.
DR STRING; 10090.ENSMUSP00000071426; -.
DR iPTMnet; Q9CR98; -.
DR PhosphoSitePlus; Q9CR98; -.
DR EPD; Q9CR98; -.
DR jPOST; Q9CR98; -.
DR MaxQB; Q9CR98; -.
DR PaxDb; Q9CR98; -.
DR PeptideAtlas; Q9CR98; -.
DR PRIDE; Q9CR98; -.
DR ProteomicsDB; 271520; -.
DR Antibodypedia; 31110; 52 antibodies from 12 providers.
DR DNASU; 66488; -.
DR Ensembl; ENSMUST00000071492; ENSMUSP00000071426; ENSMUSG00000057497.
DR GeneID; 66488; -.
DR KEGG; mmu:66488; -.
DR UCSC; uc009crl.1; mouse.
DR CTD; 84908; -.
DR MGI; MGI:1913738; Fam136a.
DR VEuPathDB; HostDB:ENSMUSG00000057497; -.
DR eggNOG; KOG3377; Eukaryota.
DR GeneTree; ENSGT00390000006707; -.
DR HOGENOM; CLU_110442_3_0_1; -.
DR InParanoid; Q9CR98; -.
DR OMA; KEMEGCV; -.
DR OrthoDB; 1456794at2759; -.
DR PhylomeDB; Q9CR98; -.
DR TreeFam; TF315119; -.
DR BioGRID-ORCS; 66488; 6 hits in 72 CRISPR screens.
DR ChiTaRS; Fam136a; mouse.
DR PRO; PR:Q9CR98; -.
DR Proteomes; UP000000589; Chromosome 6.
DR RNAct; Q9CR98; protein.
DR Bgee; ENSMUSG00000057497; Expressed in primitive streak and 265 other tissues.
DR ExpressionAtlas; Q9CR98; baseline and differential.
DR Genevisible; Q9CR98; MM.
DR GO; GO:0005737; C:cytoplasm; ISO:MGI.
DR GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR InterPro; IPR008560; DUF842_euk.
DR PANTHER; PTHR21096; PTHR21096; 1.
DR Pfam; PF05811; DUF842; 1.
PE 1: Evidence at protein level;
KW Acetylation; Phosphoprotein; Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250|UniProtKB:Q96C01"
FT CHAIN 2..138
FT /note="Protein FAM136A"
FT /id="PRO_0000296951"
FT MOD_RES 2
FT /note="N-acetylalanine"
FT /evidence="ECO:0000250|UniProtKB:Q96C01"
FT MOD_RES 124
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:B0BN94"
FT MOD_RES 126
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:B0BN94"
SQ SEQUENCE 138 AA; 15674 MW; 0C1B2E33C7D8BDB6 CRC64;
MAEVQQLRVQ EAVDAMVKSV ERENIRKMQG LMFRCSANCC EDTQASMQQV HQCIERCHAP
LAQAQALVTS ELERFQDRLA RCTMHCNDKA KDSMDAGTKE LQVKRQLDSC VTKCVDDHMH
LIPTMTKKMK ESLSSIGK
