AHL9_ARATH
ID AHL9_ARATH Reviewed; 348 AA.
AC O80834;
DT 04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 135.
DE RecName: Full=AT-hook motif nuclear-localized protein 9 {ECO:0000312|EMBL:FAA00280.1};
GN Name=AHL9 {ECO:0000303|PubMed:15604740};
GN OrderedLocusNames=At2g45850 {ECO:0000312|Araport:AT2G45850};
GN ORFNames=F4I18.17 {ECO:0000312|EMBL:AAC28539.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP IDENTIFICATION, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=15604740; DOI=10.1007/s11103-004-3249-5;
RA Fujimoto S., Matsunaga S., Yonemura M., Uchiyama S., Azuma T., Fukui K.;
RT "Identification of a novel plant MAR DNA binding protein localized on
RT chromosomal surfaces.";
RL Plant Mol. Biol. 56:225-239(2004).
RN [5]
RP GENE FAMILY, AND DOMAIN PPC.
RX PubMed=24218605; DOI=10.1073/pnas.1219277110;
RA Zhao J., Favero D.S., Peng H., Neff M.M.;
RT "Arabidopsis thaliana AHL family modulates hypocotyl growth redundantly by
RT interacting with each other via the PPC/DUF296 domain.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:E4688-E4697(2013).
CC -!- FUNCTION: Transcription factor that specifically binds AT-rich DNA
CC sequences related to the nuclear matrix attachment regions (MARs).
CC {ECO:0000250|UniProtKB:Q8VYJ2}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8VYJ2}.
CC -!- DOMAIN: The PPC domain mediates interactions between AHL proteins.
CC {ECO:0000269|PubMed:24218605}.
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DR EMBL; AC004665; AAC28539.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC10609.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC10610.1; -; Genomic_DNA.
DR EMBL; AF367271; AAK56260.1; -; mRNA.
DR EMBL; AY059157; AAL15382.1; -; mRNA.
DR EMBL; AY062699; AAL32777.1; -; mRNA.
DR EMBL; AY114678; AAM47997.1; -; mRNA.
DR EMBL; BR000345; FAA00280.1; -; mRNA.
DR PIR; T02462; T02462.
DR RefSeq; NP_182109.1; NM_130148.3.
DR RefSeq; NP_850442.1; NM_180111.2.
DR AlphaFoldDB; O80834; -.
DR SMR; O80834; -.
DR IntAct; O80834; 7.
DR STRING; 3702.AT2G45850.1; -.
DR iPTMnet; O80834; -.
DR PaxDb; O80834; -.
DR PRIDE; O80834; -.
DR ProteomicsDB; 244802; -.
DR EnsemblPlants; AT2G45850.1; AT2G45850.1; AT2G45850.
DR EnsemblPlants; AT2G45850.2; AT2G45850.2; AT2G45850.
DR GeneID; 819193; -.
DR Gramene; AT2G45850.1; AT2G45850.1; AT2G45850.
DR Gramene; AT2G45850.2; AT2G45850.2; AT2G45850.
DR KEGG; ath:AT2G45850; -.
DR Araport; AT2G45850; -.
DR TAIR; locus:2050766; AT2G45850.
DR eggNOG; ENOG502QTYW; Eukaryota.
DR HOGENOM; CLU_039808_0_2_1; -.
DR InParanoid; O80834; -.
DR OrthoDB; 1218793at2759; -.
DR PhylomeDB; O80834; -.
DR PRO; PR:O80834; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O80834; baseline and differential.
DR Genevisible; O80834; AT.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0003680; F:minor groove of adenine-thymine-rich DNA binding; IEA:InterPro.
DR CDD; cd11378; DUF296; 1.
DR InterPro; IPR039605; AHL.
DR InterPro; IPR017956; AT_hook_DNA-bd_motif.
DR InterPro; IPR005175; PPC_dom.
DR PANTHER; PTHR31500; PTHR31500; 1.
DR Pfam; PF03479; PCC; 1.
DR SMART; SM00384; AT_hook; 2.
DR PROSITE; PS51742; PPC; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..348
FT /note="AT-hook motif nuclear-localized protein 9"
FT /id="PRO_0000432027"
FT DOMAIN 157..299
FT /note="PPC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01078"
FT DNA_BIND 98..110
FT /note="A.T hook 1"
FT /evidence="ECO:0000255"
FT DNA_BIND 132..144
FT /note="A.T hook 2"
FT /evidence="ECO:0000255"
FT REGION 18..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 98..106
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000305"
FT COMPBIAS 27..60
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 348 AA; 36335 MW; 91340BCEF87B114D CRC64;
MDRRDAMGLS GSGSYYIHRG LSGSGPPTFH GSPQQQQGLR HLPNQNSPFG SGSTGFGSPS
LHGDPSLATA AGGAGALPHH IGVNMIAPPP PPSETPMKRK RGRPRKYGQD GSVSLALSSS
SVSTITPNNS NKRGRGRPPG SGKKQRMASV GELMPSSSGM SFTPHVIAVS IGEDIASKVI
AFSQQGPRAI CVLSASGAVS TATLIQPSAS PGAIKYEGRF EILALSTSYI VATDGSFRNR
TGNLSVSLAS PDGRVIGGAI GGPLIAASPV QVIVGSFIWA APKIKSKKRE EEASEVVQET
DDHHVLDNNN NTISPVPQQQ PNQNLIWSTG SRQMDMRHAH ADIDLMRG
