F151A_DANRE
ID F151A_DANRE Reviewed; 599 AA.
AC A5PN38;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 10-JUL-2007, sequence version 1.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=Protein FAM151A;
GN Name=fam151a; ORFNames=si:ch211-215b16.4;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the FAM151 family. {ECO:0000305}.
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DR EMBL; BX927315; CAN88065.1; -; Genomic_DNA.
DR RefSeq; NP_001093565.1; NM_001100095.1.
DR AlphaFoldDB; A5PN38; -.
DR STRING; 7955.ENSDARP00000075469; -.
DR PaxDb; A5PN38; -.
DR Ensembl; ENSDART00000081026; ENSDARP00000075469; ENSDARG00000058218.
DR GeneID; 100005645; -.
DR KEGG; dre:100005645; -.
DR CTD; 338094; -.
DR ZFIN; ZDB-GENE-070705-105; fam151a.
DR eggNOG; KOG3748; Eukaryota.
DR GeneTree; ENSGT00530000063681; -.
DR InParanoid; A5PN38; -.
DR OrthoDB; 1117332at2759; -.
DR PhylomeDB; A5PN38; -.
DR TreeFam; TF315079; -.
DR PRO; PR:A5PN38; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 2.
DR Bgee; ENSDARG00000058218; Expressed in intestine and 6 other tissues.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR019356; DUF2181.
DR PANTHER; PTHR21184; PTHR21184; 1.
DR Pfam; PF10223; DUF2181; 2.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..599
FT /note="Protein FAM151A"
FT /id="PRO_0000397672"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 599 AA; 68041 MW; 01ED3E09F7607E4C CRC64;
MEVKEEKSCS IGEGEEAEGK EAKTVLGIFT REQFIMLCVG LGLIALLLII TLTSVFVIAK
SDASVDVDME PFPSDGDMLD FLLQTGEIEE KDGLYATWYH AANSKSEMSK ALNSDVMILE
ADVNVQGHNT VNETNIPIMA HPPDIYSDNT LEEWLDAVLK SKKGVKLDFK SISAVEPSLD
LLRAKNQTGI NRPVWINADI LPGPNVPEFW PVVNASEFFE LIQLKFPDVT ISPGWKVLYL
SIFPNVTYTR SMVEQMYSTI RHLPQKITFP VHALMAKNGW PHLSWLLSQS SRYSLTLWQG
KENPTLNDLL FIRDNSNPQR IYYDIYEPVL SQFREAAKIK DRPRRFYPGG DIVDYFRPAD
SDGLNIQWDT VNDKDSLLSL LEDSPGGMLV IPVKSSDGHP NIPIIDGSEM PLKDCLDLIL
ASTKPWGIYL QIKSQNQLSL SLELLRQAYD IDLLHHPTWV NMDISHGAVH IQGYMTGEEF
LRTVDRIFPH VTLAPSWPKE ALVEGYTPEM LEPMVQLFHR AWQDVSLQLQ AEALDRSETW
RLVLVQPRFS LTVEHQTENK DINAGIESLM AIRAANRQRS FYNIPKMYRE HITDLSVRK