F151A_MOUSE
ID F151A_MOUSE Reviewed; 608 AA.
AC Q8QZW3;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Protein FAM151A;
GN Name=Fam151a;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=C57BL/6J; TISSUE=Pancreas;
RA Wang J., Cao Y., Gardner P., Steiner D.F.;
RL Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Kidney;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Kidney;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the FAM151 family. {ECO:0000305}.
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DR EMBL; AY168619; AAO38748.1; -; mRNA.
DR EMBL; AL929585; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC024426; AAH24426.1; -; mRNA.
DR EMBL; BC024430; AAH24430.1; -; mRNA.
DR EMBL; BC026682; AAH26682.1; -; mRNA.
DR CCDS; CCDS18425.1; -.
DR RefSeq; NP_666261.1; NM_146149.1.
DR AlphaFoldDB; Q8QZW3; -.
DR STRING; 10090.ENSMUSP00000047860; -.
DR PhosphoSitePlus; Q8QZW3; -.
DR jPOST; Q8QZW3; -.
DR MaxQB; Q8QZW3; -.
DR PaxDb; Q8QZW3; -.
DR PRIDE; Q8QZW3; -.
DR ProteomicsDB; 275970; -.
DR Antibodypedia; 52799; 72 antibodies from 14 providers.
DR Ensembl; ENSMUST00000047620; ENSMUSP00000047860; ENSMUSG00000034871.
DR GeneID; 230579; -.
DR KEGG; mmu:230579; -.
DR UCSC; uc008tyu.1; mouse.
DR CTD; 338094; -.
DR MGI; MGI:2657115; Fam151a.
DR VEuPathDB; HostDB:ENSMUSG00000034871; -.
DR eggNOG; KOG3748; Eukaryota.
DR GeneTree; ENSGT00530000063681; -.
DR HOGENOM; CLU_033162_2_0_1; -.
DR InParanoid; Q8QZW3; -.
DR OMA; CRPDADM; -.
DR OrthoDB; 1117332at2759; -.
DR PhylomeDB; Q8QZW3; -.
DR TreeFam; TF315079; -.
DR BioGRID-ORCS; 230579; 7 hits in 72 CRISPR screens.
DR ChiTaRS; Fam151a; mouse.
DR PRO; PR:Q8QZW3; -.
DR Proteomes; UP000000589; Chromosome 4.
DR RNAct; Q8QZW3; protein.
DR Bgee; ENSMUSG00000034871; Expressed in right kidney and 57 other tissues.
DR Genevisible; Q8QZW3; MM.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR019356; DUF2181.
DR PANTHER; PTHR21184; PTHR21184; 1.
DR Pfam; PF10223; DUF2181; 2.
PE 1: Evidence at protein level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..608
FT /note="Protein FAM151A"
FT /id="PRO_0000310956"
FT TRANSMEM 14..34
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 586..608
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 608 AA; 66681 MW; E7166AA33116A225 CRC64;
MSCKKWCSSS QAKWILAGSV TVTLVLAISL ILGLTLHQGT QPGCENDAIC GPDADMLDYL
MGMGQISHRD GLLVTWYHAA NSKKEMAAAL NSDVMVLEAD VTVEGFNTAN ETKVPIMAHP
PAIYSDNTLQ EWLEAVLASS QKGIKLDFKS LKAVGPSLDL LRQLTEAGRI RRPVWINADI
LRGPNVPISI EINATQFLTL VQEKYPKATI SPGFTTLYVP QLPNSTYTQA MVETMQELVG
ALPQKVTFPV RAVMTRAAWP HFSWLLSQSE RYSLTLWQGA SDPVSVEDLL FIRDNSAAHQ
IYYDLFEPVL SQFKQLALNT TRKRTYYTGG SLIPLLQQPK GDGLEVEWLV LEVNGSGRRA
AITVPDREGM ILLDIGLQEP EAGNPVPILH TPGGPALTLE SCLLRLAVHP RRWGIHVNIV
EPEALRPSLA TLAHLSTLGH LPWPVWVGST VSHGSFVVPG HIAGRELLTA VAEVFPHVTV
APGWPEEMLD SGYQEQMVTD MLELCQGLRQ PVSFQLQAGP LSQSPANTVA RLLASSPRAT
VTVYHSTAGN SHVDLWAGLW AARAVDRTRV YYRISQEYWK DLQADVSSNR PSSRIGPSSV
EGFPGESR