ID   F157A_HUMAN             Reviewed;         383 AA.
AC   C9JC47;
DT   13-JUL-2010, integrated into UniProtKB/Swiss-Prot.
DT   03-NOV-2009, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Putative protein FAM157A;
GN   Name=FAM157A;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA   Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA   Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA   Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA   Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA   Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA   Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA   Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA   Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA   Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA   Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA   Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA   Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O.,
RA   Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X.,
RA   Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA   Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
CC   -!- SIMILARITY: Belongs to the FAM157 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC073135; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001138720.1; NM_001145248.1.
DR   RefSeq; XP_016862614.1; XM_017007125.1.
DR   AlphaFoldDB; C9JC47; -.
DR   BioGRID; 608692; 1.
DR   iPTMnet; C9JC47; -.
DR   PhosphoSitePlus; C9JC47; -.
DR   BioMuta; HGNC:34079; -.
DR   PaxDb; C9JC47; -.
DR   PeptideAtlas; C9JC47; -.
DR   PRIDE; C9JC47; -.
DR   GeneCards; FAM157A; -.
DR   HGNC; HGNC:34079; FAM157A.
DR   neXtProt; NX_C9JC47; -.
DR   PharmGKB; PA164719690; -.
DR   InParanoid; C9JC47; -.
DR   PhylomeDB; C9JC47; -.
DR   PathwayCommons; C9JC47; -.
DR   BioGRID-ORCS; 728262; 31 hits in 178 CRISPR screens.
DR   GenomeRNAi; 728262; -.
DR   Pharos; C9JC47; Tdark.
DR   PRO; PR:C9JC47; -.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; C9JC47; protein.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..383
FT                   /note="Putative protein FAM157A"
FT                   /id="PRO_0000395456"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          177..254
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   383 AA;  42896 MW;  EE2D0B1AA8088917 CRC64;
     MGPLFTTIPG AHSGPMRPLP KKHVEPMAVR QLLLGNSTMI RHTCPMSVPL SRQVKEVAAQ
     KPSEDIYKNW QQQQQQQQQQ QQQQLDLLFH QRIQISLWPR KQKRRKTEQH SHPFVKKAFR
     FSAGSGCGRP SSNKMLRSMG GGQRPTGLGS EFFRLLHDLH LLAFAMKRIW IHRRGEATAR
     PRAPEHPAPP ATAVRGRDAA SQNLKRRPGS GTDGLRLQGA EPSRLLRTYA GGAVIPTGTP
     ERAQPPPPQD PLGRRRWLSR NTWGPWPGTT QPPSPQLLRN DWGSCGFMVP EAARGKVFQD
     SQEGAHIRRE TVSKSVCAEP WRHQRARDPA PTNFPLRCQK QRGASASSGQ HEGRVNLVFF
     IGSPTVIAVP DLQCPTKYSG MLY