ID   F157B_HUMAN             Reviewed;         384 AA.
AC   P0CG42;
DT   13-JUL-2010, integrated into UniProtKB/Swiss-Prot.
DT   13-JUL-2010, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Putative protein FAM157B;
GN   Name=FAM157B;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15164053; DOI=10.1038/nature02465;
RA   Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L.,
RA   Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R.,
RA   Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S.,
RA   Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K.,
RA   Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y.,
RA   Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C.,
RA   Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E.,
RA   Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M.,
RA   Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J.,
RA   Frankish A., Frankland J.A., French L., Fricker D.G., Garner P.,
RA   Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S.,
RA   Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E.,
RA   Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D.,
RA   Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E.,
RA   Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K.,
RA   Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S.,
RA   Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J.,
RA   Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E.,
RA   McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V.,
RA   Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S.,
RA   Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K.,
RA   Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J.,
RA   Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M.,
RA   West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L.,
RA   Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M.,
RA   Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J.,
RA   Dunham I.;
RT   "DNA sequence and analysis of human chromosome 9.";
RL   Nature 429:369-374(2004).
CC   -!- SIMILARITY: Belongs to the FAM157 family. {ECO:0000305}.
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DR   EMBL; AL954642; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001138721.1; NM_001145249.1.
DR   RefSeq; XP_011516415.1; XM_011518113.2.
DR   AlphaFoldDB; P0CG42; -.
DR   BioGRID; 935804; 1.
DR   IntAct; P0CG42; 1.
DR   iPTMnet; P0CG42; -.
DR   PhosphoSitePlus; P0CG42; -.
DR   BioMuta; HGNC:34080; -.
DR   DMDM; 300680942; -.
DR   MassIVE; P0CG42; -.
DR   PRIDE; P0CG42; -.
DR   GeneCards; FAM157B; -.
DR   HGNC; HGNC:34080; FAM157B.
DR   neXtProt; NX_P0CG42; -.
DR   PharmGKB; PA164719708; -.
DR   InParanoid; P0CG42; -.
DR   PhylomeDB; P0CG42; -.
DR   PathwayCommons; P0CG42; -.
DR   SignaLink; P0CG42; -.
DR   BioGRID-ORCS; 100132403; 17 hits in 183 CRISPR screens.
DR   ChiTaRS; FAM157B; human.
DR   GenomeRNAi; 100132403; -.
DR   Pharos; P0CG42; Tdark.
DR   PRO; PR:P0CG42; -.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; P0CG42; protein.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..384
FT                   /note="Putative protein FAM157B"
FT                   /id="PRO_0000395457"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          60..84
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          177..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          326..350
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   384 AA;  43129 MW;  DCA4FD587D9A89EE CRC64;
     MGPLFTTIPG AHSGPMRPLP KKHVEPMAVR QLLLGNSTMI RHTCPMSVPL SRQVKEVAAQ
     KPSEDIYKNR QRRQQQQQQQ QQQQQLDLLF HQRIQISLWP RKQKRRKTEQ HSHPFVKKAF
     RFSAGPGCRR PSSNKMLRSM GGGQRPMGLG SEFFRLLHDL HLLAFATKRI WIHRRGEATA
     RPRAPEHPAP PATAVRGRDA ASQNLKRRPG SGTDGLRLQG AEPSRLLRTY AGGAVIPTGT
     PERAQPPPPQ DPLGRRRWLS RNTWGPWPGT TQPPSPQLLR NDWGSCGFMV PEAARGKVFQ
     DSQEGAHIRR ETVSKSVCAE PWRHQRARDP APTNFPLKCQ KQRGASTSSG QHGGRVNLVF
     FIDSPTVIAV PDLQCPTKYS GILY