ID   F161A_XENTR             Reviewed;         659 AA.
AC   B0BM24;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Protein FAM161A;
GN   Name=fam161a;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in ciliogenesis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body
CC       {ECO:0000250}. Cell projection, cilium {ECO:0000250}. Note=Localized in
CC       the region between the outer and inner photoreceptor segments,
CC       corresponding to the photoreceptor connecting cilium. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FAM161 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC158257; AAI58258.1; -; mRNA.
DR   RefSeq; NP_001119995.1; NM_001126523.1.
DR   AlphaFoldDB; B0BM24; -.
DR   SMR; B0BM24; -.
DR   STRING; 8364.ENSXETP00000064127; -.
DR   PaxDb; B0BM24; -.
DR   GeneID; 100144951; -.
DR   KEGG; xtr:100144951; -.
DR   CTD; 84140; -.
DR   eggNOG; ENOG502QRC3; Eukaryota.
DR   InParanoid; B0BM24; -.
DR   OMA; MWDDFSV; -.
DR   OrthoDB; 1085171at2759; -.
DR   PhylomeDB; B0BM24; -.
DR   TreeFam; TF321199; -.
DR   Proteomes; UP000008143; Chromosome 5.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000002233; Expressed in 4-cell stage embryo and 6 other tissues.
DR   GO; GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   InterPro; IPR019579; FAM161A/B.
DR   Pfam; PF10595; UPF0564; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Cilium biogenesis/degradation; Coiled coil;
KW   Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..659
FT                   /note="Protein FAM161A"
FT                   /id="PRO_0000329056"
FT   REGION          34..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          165..190
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          401..428
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          594..659
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          96..120
FT                   /evidence="ECO:0000255"
FT   COILED          531..557
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        39..53
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        165..179
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        638..659
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   659 AA;  75989 MW;  FA7BD82C05D78880 CRC64;
     MAQAHKESVL AAACVRTPVN PYTKAPLALY ERELGERQQQ RTASVSPQRL PRTSMGTPAA
     PAAALDWEEA RCCKSRRCQD WVFDISKVHH PDKDYYVQVE KLKKAHLQNM EQLEKMYDKK
     LHLSGVHNPE NEQGVVREVY RSAWEPKSVL PAEYDDKYLK HSLSGSVSPS LSESSHESTN
     GDSSDSEHSV SARNKILDMW NEFTVEDYIR NSEYFSKEIA KNKTSKKSKE WSHKITIPEP
     FQMTIRESKK KEMNIKSKSE IELENNLLKK KLEEEAECQK KFRANPVPSS VYLPLYQEIV
     ERNEERRSFV KEKSKDILLA TQKPFQFIER EERKKTLRLD FMNLSTSVPS ANHFKAKPVP
     KSIYGTSTAE RLKEEELYRG IRIHMRAQEL LQNSSYPTIT LAPGAHSGTK KGKCYKPKEK
     QKHKPKISAT IPHSQTMHEN QQKRLPESTS TKHVTVCEPF QLRTSNIPSH KEKIIMDIQA
     DEENLKETRW PYKSPRAQAR IHSSAGTLNP QGEALCNIPR STELSKRREH AIRKREKQRT
     KDYMKELEAM EQRVLNKPLL IERVAQRNAL MSAEKQYLNV LRDLGLSEEF VSKNGQSASV
     DEHVSVREEN NPRAESTEGT LVLEDLLDDA EKYQTDPESE EAQEEDAYST DEDHSMEEI