F163A_MOUSE
ID F163A_MOUSE Reviewed; 168 AA.
AC Q8CAA5;
DT 20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Protein FAM163A;
GN Name=Fam163a;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Hypothalamus;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the FAM163 family. {ECO:0000305}.
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DR EMBL; AK039197; BAC30275.1; -; mRNA.
DR EMBL; BC116972; AAI16973.1; -; mRNA.
DR EMBL; BC116974; AAI16975.1; -; mRNA.
DR CCDS; CCDS15390.1; -.
DR RefSeq; NP_808506.1; NM_177838.3.
DR RefSeq; XP_017176771.1; XM_017321282.1.
DR RefSeq; XP_017176772.1; XM_017321283.1.
DR RefSeq; XP_017176773.1; XM_017321284.1.
DR AlphaFoldDB; Q8CAA5; -.
DR SMR; Q8CAA5; -.
DR STRING; 10090.ENSMUSP00000015628; -.
DR iPTMnet; Q8CAA5; -.
DR PhosphoSitePlus; Q8CAA5; -.
DR PaxDb; Q8CAA5; -.
DR PRIDE; Q8CAA5; -.
DR ProteomicsDB; 271524; -.
DR Antibodypedia; 2490; 112 antibodies from 17 providers.
DR DNASU; 329274; -.
DR Ensembl; ENSMUST00000015628; ENSMUSP00000015628; ENSMUSG00000015484.
DR GeneID; 329274; -.
DR KEGG; mmu:329274; -.
DR UCSC; uc033fmn.1; mouse.
DR CTD; 148753; -.
DR MGI; MGI:3618859; Fam163a.
DR VEuPathDB; HostDB:ENSMUSG00000015484; -.
DR eggNOG; ENOG502S10V; Eukaryota.
DR GeneTree; ENSGT00940000159228; -.
DR HOGENOM; CLU_138617_0_0_1; -.
DR InParanoid; Q8CAA5; -.
DR OMA; CNACSSR; -.
DR OrthoDB; 1417278at2759; -.
DR PhylomeDB; Q8CAA5; -.
DR TreeFam; TF333084; -.
DR BioGRID-ORCS; 329274; 1 hit in 61 CRISPR screens.
DR ChiTaRS; Fam163a; mouse.
DR PRO; PR:Q8CAA5; -.
DR Proteomes; UP000000589; Chromosome 1.
DR RNAct; Q8CAA5; protein.
DR Bgee; ENSMUSG00000015484; Expressed in right kidney and 45 other tissues.
DR ExpressionAtlas; Q8CAA5; baseline and differential.
DR Genevisible; Q8CAA5; MM.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR029379; FAM163.
DR InterPro; IPR040281; FAM163A.
DR PANTHER; PTHR31914; PTHR31914; 1.
DR Pfam; PF15069; FAM163; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..168
FT /note="Protein FAM163A"
FT /id="PRO_0000280257"
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 168 AA; 17839 MW; 414769B3494D3CC5 CRC64;
MTAGTVVITG GILATVILLC IIAVLCYCRL QYYCCKKGTD GEDAEEEEEE EEHGLSIHPR
VPACNACSSH VLDGRGGLAP LTSESCSQPC GVASHCTTCS PYRTPFYIRT ADMVPNGGGG
ERLSFAPTHY KEGGTPSLKL AAPQNYPVTW PSSGHEAFTN PRAISTDV
