F166A_MOUSE
ID F166A_MOUSE Reviewed; 319 AA.
AC Q9D4K5;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Protein FAM166A;
GN Name=Fam166a;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the UPF0605 family. {ECO:0000305}.
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DR EMBL; AK016459; BAB30248.1; -; mRNA.
DR EMBL; AL732309; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC061039; AAH61039.1; -; mRNA.
DR CCDS; CCDS15752.1; -.
DR RefSeq; NP_080900.1; NM_026624.3.
DR RefSeq; XP_006498331.1; XM_006498268.3.
DR AlphaFoldDB; Q9D4K5; -.
DR STRING; 10090.ENSMUSP00000028346; -.
DR PhosphoSitePlus; Q9D4K5; -.
DR PaxDb; Q9D4K5; -.
DR PRIDE; Q9D4K5; -.
DR ProteomicsDB; 275971; -.
DR Antibodypedia; 18988; 66 antibodies from 13 providers.
DR Ensembl; ENSMUST00000028346; ENSMUSP00000028346; ENSMUSG00000026969.
DR GeneID; 68222; -.
DR KEGG; mmu:68222; -.
DR UCSC; uc008iqr.2; mouse.
DR CTD; 401565; -.
DR MGI; MGI:3605773; Fam166a.
DR VEuPathDB; HostDB:ENSMUSG00000026969; -.
DR eggNOG; ENOG502QSNH; Eukaryota.
DR GeneTree; ENSGT00730000111343; -.
DR HOGENOM; CLU_076252_0_0_1; -.
DR InParanoid; Q9D4K5; -.
DR OMA; YAGFIPR; -.
DR OrthoDB; 851402at2759; -.
DR PhylomeDB; Q9D4K5; -.
DR TreeFam; TF336316; -.
DR BioGRID-ORCS; 68222; 4 hits in 75 CRISPR screens.
DR PRO; PR:Q9D4K5; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q9D4K5; protein.
DR Bgee; ENSMUSG00000026969; Expressed in seminiferous tubule of testis and 56 other tissues.
DR Genevisible; Q9D4K5; MM.
DR GO; GO:0036064; C:ciliary basal body; ISO:MGI.
DR InterPro; IPR018902; FAM166/UPF0605.
DR Pfam; PF10629; DUF2475; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..319
FT /note="Protein FAM166A"
FT /id="PRO_0000325901"
SQ SEQUENCE 319 AA; 36613 MW; 48784958575D3D7A CRC64;
MTATQKHNLF TPEPHYIPGY AGFYPQLRYQ VGNTYGRTTA QLLTDPSVQK SPCSVLSPMT
KPKFIEDFSK SKPPWIPCRD LREPYIPHYT SLKPYKNFEI LGQLPRQDVD TQGPPQVENR
QGPLTAGFMP YPPYPACPPG RKGEARDLGH PGLLLAYGEE AWKDAAPLQD TPGKNNQLYH
CRRDEYLPPH PPQETLDVGR FQRLPQLDHP NLIQRKAISG YAGFVPRFAW VMGMNYRDGV
TQAMDDFDKN QFVFRHPVCA LGERLPRTHW PNTTIYRSQG LIPFYMGFIP SMQDNYALTF
GNSTRRAYQK ELDRRSHTL
