ID   F166B_DANRE             Reviewed;         299 AA.
AC   A2RRW4; Q0P4C8;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2007, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Protein FAM166B;
GN   Name=fam166b; ORFNames=zgc:158652;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Olfactory epithelium;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated
CC       doublet microtubules (DMTs) in cilia axoneme, which is required for
CC       motile cilia beating. {ECO:0000250|UniProtKB:Q2TBR5}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC       {ECO:0000250|UniProtKB:Q2TBR5}.
CC   -!- SIMILARITY: Belongs to the UPF0605 family. {ECO:0000305}.
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DR   EMBL; BC122153; AAI22154.1; -; mRNA.
DR   EMBL; BC131879; AAI31880.1; -; mRNA.
DR   AlphaFoldDB; A2RRW4; -.
DR   IntAct; A2RRW4; 2.
DR   MINT; A2RRW4; -.
DR   STRING; 7955.ENSDARP00000099646; -.
DR   PaxDb; A2RRW4; -.
DR   PeptideAtlas; A2RRW4; -.
DR   ZFIN; ZDB-GENE-070209-41; fam166b.
DR   eggNOG; ENOG502RTSD; Eukaryota.
DR   InParanoid; A2RRW4; -.
DR   PhylomeDB; A2RRW4; -.
DR   PRO; PR:A2RRW4; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005879; C:axonemal microtubule; ISS:UniProtKB.
DR   InterPro; IPR018902; FAM166/UPF0605.
DR   Pfam; PF10629; DUF2475; 2.
PE   2: Evidence at transcript level;
KW   Cell projection; Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..299
FT                   /note="Protein FAM166B"
FT                   /id="PRO_0000342385"
FT   CONFLICT        99
FT                   /note="V -> A (in Ref. 1; AAI22154)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        243
FT                   /note="N -> D (in Ref. 1; AAI22154)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   299 AA;  33273 MW;  363121DF000EF108 CRC64;
     MDLFPPKFSK VLVTPDPQYI PGYAGYCPQL KYHVGQTYGQ LTAKLLTSPE VSHSQRLVLQ
     TSPLSSTEKE TASRSQIWWS RHGASRNLET MIPGYTGFVP LRQNYICKTY AETCRDALSE
     FNQGQAKRLH NASADLSFPV INSVPDFRPR RSNSPLIALS KDPAPYKAPD PWKPPGSPYF
     MEDSSPHKYF ISGFTGYVPK ARFLFGTGYP TITNKALIQF SKEMKAGPAS LQKYSLQEED
     SSNLPLIPTI YPSKTGLLPS YTGHIPGYRF QYGHTFGKLT HNALGHTASQ KNAGAIRLS