ID   F166B_XENLA             Reviewed;         311 AA.
AC   A9JS51;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 33.
DE   RecName: Full=Protein FAM166B;
GN   Name=fam166b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated
CC       doublet microtubules (DMTs) in cilia axoneme, which is required for
CC       motile cilia beating. {ECO:0000250|UniProtKB:Q2TBR5}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC       {ECO:0000250|UniProtKB:Q2TBR5}.
CC   -!- SIMILARITY: Belongs to the UPF0605 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC155919; AAI55920.1; -; mRNA.
DR   RefSeq; NP_001106345.1; NM_001112874.1.
DR   AlphaFoldDB; A9JS51; -.
DR   GeneID; 100127307; -.
DR   KEGG; xla:100127307; -.
DR   CTD; 100127307; -.
DR   Xenbase; XB-GENE-6252437; fam166b.S.
DR   OrthoDB; 851402at2759; -.
DR   Proteomes; UP000186698; Chromosome 1S.
DR   Bgee; 100127307; Expressed in neurula embryo and 10 other tissues.
DR   GO; GO:0005879; C:axonemal microtubule; ISS:UniProtKB.
DR   InterPro; IPR018902; FAM166/UPF0605.
DR   Pfam; PF10629; DUF2475; 3.
PE   2: Evidence at transcript level;
KW   Cell projection; Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..311
FT                   /note="Protein FAM166B"
FT                   /id="PRO_0000342386"
FT   REGION          64..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          150..183
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   311 AA;  35489 MW;  3EB22FFEEFB5E068 CRC64;
     MAVTFPPKIS PTLMTPDPHF IPGYSGFCPQ YRYSLGKTYG QLTSHLLTNP DIRRSGHLVL
     QSNPFPPAPR GHSYNEASQE LGGRRRRQRL GDPKLTISMI PGYTGFIPRS QKFFAKTYAE
     TSWDALSDFH NEQQMQESQR QEMLLTSKLQ EGRQPQTEHE KQLLTARHRT PLPALSKEPA
     PFMSLRGFQP QGSPYYMEEE NPNKYFISGY TGYVPRSRFL IGNGYPITTN RAMVEFAHMN
     QKKGVRFSDQ QGHNEGDNLH TEQGQIYLEE LGLLPRYTGY VPGYKFQFGN TFGRLTQNAL
     GQSTLQKQTV N