F166B_XENTR
ID F166B_XENTR Reviewed; 306 AA.
AC A8E5W8;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 13-NOV-2007, sequence version 1.
DT 03-AUG-2022, entry version 40.
DE RecName: Full=Protein FAM166B;
GN Name=fam166b;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Thymus;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated
CC doublet microtubules (DMTs) in cilia axoneme, which is required for
CC motile cilia beating. {ECO:0000250|UniProtKB:Q2TBR5}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC {ECO:0000250|UniProtKB:Q2TBR5}.
CC -!- SIMILARITY: Belongs to the UPF0605 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC153746; AAI53747.1; -; mRNA.
DR RefSeq; NP_001106452.1; NM_001112981.1.
DR AlphaFoldDB; A8E5W8; -.
DR PaxDb; A8E5W8; -.
DR DNASU; 100127629; -.
DR GeneID; 100127629; -.
DR KEGG; xtr:100127629; -.
DR CTD; 730112; -.
DR Xenbase; XB-GENE-6456701; fam166b.
DR HOGENOM; CLU_2283983_0_0_1; -.
DR InParanoid; A8E5W8; -.
DR OrthoDB; 851402at2759; -.
DR Proteomes; UP000008143; Chromosome 1.
DR Proteomes; UP000790000; Unplaced.
DR GO; GO:0005879; C:axonemal microtubule; ISS:UniProtKB.
DR InterPro; IPR018902; FAM166/UPF0605.
DR Pfam; PF10629; DUF2475; 3.
PE 2: Evidence at transcript level;
KW Cell projection; Cytoplasm; Cytoskeleton; Reference proteome.
FT CHAIN 1..306
FT /note="Protein FAM166B"
FT /id="PRO_0000342387"
FT REGION 61..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 306 AA; 34477 MW; C3AF36AA1573DE40 CRC64;
MAGTFPPKIS PTLMTPDPHF IPGYSGFCPQ YRYSLGKTYG QLTSQLLTNP DIRRSELLVL
QSNPFPPPRD HSFDGGSQEL GGRRQHPGDP NLTISMIPGY TGFIPRSQKF FAKTYAETSR
DALSDFHSER RGQEAQRQEL LLMSKLQEGR LPRTEQEKQL LASRHRTPLP ALAKEPAPFM
ALRGFQPQGS PYYMEEENPN KCFISGYTGY VPRSRFLIGS GYPITTNRAM VEFAHMNQKK
GVRFSEGYKE GGSPHTEPGQ IYLEELGLLP RYTGYVPGYK FQFGNTFGRL TQNALGHSTL
QKQTVN