F166C_MOUSE
ID F166C_MOUSE Reviewed; 200 AA.
AC Q9DAS2; Q9D9M8;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Protein FAM166C {ECO:0000305};
GN Name=Fam166c;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9DAS2-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9DAS2-2; Sequence=VSP_033372, VSP_033373;
CC -!- SIMILARITY: Belongs to the FAM166C family. {ECO:0000305}.
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DR EMBL; AK005574; BAB24132.1; -; mRNA.
DR EMBL; AK006710; BAB24710.1; -; mRNA.
DR EMBL; BC060996; AAH60996.1; -; mRNA.
DR CCDS; CCDS19158.1; -. [Q9DAS2-1]
DR RefSeq; NP_083561.1; NM_029285.1. [Q9DAS2-1]
DR AlphaFoldDB; Q9DAS2; -.
DR STRING; 10090.ENSMUSP00000031078; -.
DR iPTMnet; Q9DAS2; -.
DR PhosphoSitePlus; Q9DAS2; -.
DR MaxQB; Q9DAS2; -.
DR PaxDb; Q9DAS2; -.
DR PRIDE; Q9DAS2; -.
DR Antibodypedia; 67330; 19 antibodies from 8 providers.
DR DNASU; 75434; -.
DR Ensembl; ENSMUST00000031078; ENSMUSP00000031078; ENSMUSG00000029182. [Q9DAS2-1]
DR Ensembl; ENSMUST00000127815; ENSMUSP00000142635; ENSMUSG00000029182. [Q9DAS2-2]
DR GeneID; 75434; -.
DR KEGG; mmu:75434; -.
DR UCSC; uc008wvm.1; mouse. [Q9DAS2-2]
DR UCSC; uc008wvn.1; mouse. [Q9DAS2-1]
DR CTD; 339778; -.
DR MGI; MGI:1922684; Fam166c.
DR VEuPathDB; HostDB:ENSMUSG00000029182; -.
DR eggNOG; ENOG502S0NQ; Eukaryota.
DR GeneTree; ENSGT00390000018634; -.
DR HOGENOM; CLU_118165_0_0_1; -.
DR InParanoid; Q9DAS2; -.
DR OMA; YQDKTGM; -.
DR OrthoDB; 1389489at2759; -.
DR PhylomeDB; Q9DAS2; -.
DR TreeFam; TF329317; -.
DR BioGRID-ORCS; 75434; 1 hit in 74 CRISPR screens.
DR PRO; PR:Q9DAS2; -.
DR Proteomes; UP000000589; Chromosome 5.
DR RNAct; Q9DAS2; protein.
DR Bgee; ENSMUSG00000029182; Expressed in seminiferous tubule of testis and 51 other tissues.
DR ExpressionAtlas; Q9DAS2; baseline and differential.
DR Genevisible; Q9DAS2; MM.
DR InterPro; IPR018902; FAM166/UPF0605.
DR Pfam; PF10629; DUF2475; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..200
FT /note="Protein FAM166C"
FT /id="PRO_0000332278"
FT VAR_SEQ 116..117
FT /note="TV -> VS (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_033372"
FT VAR_SEQ 118..200
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_033373"
SQ SEQUENCE 200 AA; 23070 MW; 0FF559086A50F4D3 CRC64;
MAFRSAGTLM TEFNAAFVPP ALMPGYKGHV PGVASSFGSS YGNTTFKYFQ DLRNTGLEKS
YALLSGGCFP TIFSPNSPLV LTDNSQNWDR WLHQPTYSRS NQDNGRTTEL TNFYKTVQQQ
RKYYQDKTGI LSRVPYFVLP VKEPDRYPLP TDLPPLSEKS KWNLLRLSPD YKRTYQTFPS
GKRVSSQERQ RRDLYFEFRA
