F16A3_PARP8
ID F16A3_PARP8 Reviewed; 367 AA.
AC B2JX47;
DT 03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-JUN-2008, sequence version 1.
DT 25-MAY-2022, entry version 77.
DE RecName: Full=Fructose-1,6-bisphosphatase class 1 3 {ECO:0000255|HAMAP-Rule:MF_01855};
DE Short=FBPase class 1 3 {ECO:0000255|HAMAP-Rule:MF_01855};
DE EC=3.1.3.11 {ECO:0000255|HAMAP-Rule:MF_01855};
DE AltName: Full=D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 3 {ECO:0000255|HAMAP-Rule:MF_01855};
GN Name=fbp3 {ECO:0000255|HAMAP-Rule:MF_01855}; OrderedLocusNames=Bphy_6494;
OS Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 /
OS STM815) (Burkholderia phymatum).
OG Plasmid pBPHY01.
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=391038;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17167 / CIP 108236 / LMG 21445 / STM815;
RX PubMed=25197461; DOI=10.4056/sigs.4861021;
RA Moulin L., Klonowska A., Caroline B., Booth K., Vriezen J.A., Melkonian R.,
RA James E.K., Young J.P., Bena G., Hauser L., Land M., Kyrpides N., Bruce D.,
RA Chain P., Copeland A., Pitluck S., Woyke T., Lizotte-Waniewski M.,
RA Bristow J., Riley M.;
RT "Complete genome sequence of Burkholderia phymatum STM815(T), a broad host
RT range and efficient nitrogen-fixing symbiont of Mimosa species.";
RL Stand. Genomic Sci. 9:763-774(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-
CC phosphate + phosphate; Xref=Rhea:RHEA:11064, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:32966, ChEBI:CHEBI:43474, ChEBI:CHEBI:57634; EC=3.1.3.11;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01855};
CC -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC {ECO:0000255|HAMAP-Rule:MF_01855}.
CC -!- SUBUNIT: Homotetramer. {ECO:0000255|HAMAP-Rule:MF_01855}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01855}.
CC -!- SIMILARITY: Belongs to the FBPase class 1 family. {ECO:0000255|HAMAP-
CC Rule:MF_01855}.
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DR EMBL; CP001045; ACC75524.1; -; Genomic_DNA.
DR RefSeq; WP_012405683.1; NZ_CADFGH010000013.1.
DR AlphaFoldDB; B2JX47; -.
DR SMR; B2JX47; -.
DR EnsemblBacteria; ACC75524; ACC75524; Bphy_6494.
DR KEGG; bph:Bphy_6494; -.
DR HOGENOM; CLU_039977_0_0_4; -.
DR OMA; HEKSECY; -.
DR OrthoDB; 945770at2; -.
DR UniPathway; UPA00138; -.
DR Proteomes; UP000001192; Plasmid pBPHY01.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR CDD; cd00354; FBPase; 1.
DR HAMAP; MF_01855; FBPase_class1; 1.
DR InterPro; IPR044015; FBPase_C_dom.
DR InterPro; IPR000146; FBPase_class-1.
DR InterPro; IPR033391; FBPase_N.
DR InterPro; IPR028343; FBPtase.
DR PANTHER; PTHR11556; PTHR11556; 1.
DR Pfam; PF00316; FBPase; 1.
DR Pfam; PF18913; FBPase_C; 1.
DR PIRSF; PIRSF000904; FBPtase_SBPase; 1.
DR PRINTS; PR00115; F16BPHPHTASE.
PE 3: Inferred from homology;
KW Carbohydrate metabolism; Cytoplasm; Hydrolase; Plasmid; Reference proteome.
FT CHAIN 1..367
FT /note="Fructose-1,6-bisphosphatase class 1 3"
FT /id="PRO_0000364497"
SQ SEQUENCE 367 AA; 39997 MW; E4F3EDEA53FF22DA CRC64;
MRHANVTLTR FLAGDADHLM TTRPPTALQA VLHEVAASVK TIASALARGT LGDSAHADSV
AGGAVLAYAT RRRKLAETAA RNRGADDAGK PEYQLAFDPL NCPWNADING TAGSIFSVMR
VQSQGSDADG AADTCAQAYG ELDCEPYDEP YGAPFLQPGR EQAAAGYTIY GPATMLIVTL
GEGTHGFTLD GQTDEFMLTH PSIRIPAETG EIAVDASNER FWEPPVRRYV HECRDGRAGC
RERDFSLRWS DALVAEVHRI LMRGGLFLMP RDYRTRSAMR GRLSAVYDAS PLGFLVEQAG
GMATTGRERV LDAAPRTFHE RMPLILGSAS EVTRIGRYHR EHDLGIDAPF TSPLFRERSL
FLPETSL
