ID   F16PC_BACVZ             Reviewed;         641 AA.
AC   A7ZAK3;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Fructose-1,6-bisphosphatase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE            Short=FBPase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE            EC=3.1.3.11 {ECO:0000255|HAMAP-Rule:MF_01854};
DE   AltName: Full=D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
GN   Name=fbp {ECO:0000255|HAMAP-Rule:MF_01854}; OrderedLocusNames=RBAM_037000;
OS   Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42)
OS   (Bacillus amyloliquefaciens subsp. plantarum).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus amyloliquefaciens group.
OX   NCBI_TaxID=326423;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42;
RX   PubMed=17704766; DOI=10.1038/nbt1325;
RA   Chen X.H., Koumoutsi A., Scholz R., Eisenreich A., Schneider K.,
RA   Heinemeyer I., Morgenstern B., Voss B., Hess W.R., Reva O., Junge H.,
RA   Voigt B., Jungblut P.R., Vater J., Suessmuth R., Liesegang H.,
RA   Strittmatter A., Gottschalk G., Borriss R.;
RT   "Comparative analysis of the complete genome sequence of the plant growth-
RT   promoting bacterium Bacillus amyloliquefaciens FZB42.";
RL   Nat. Biotechnol. 25:1007-1014(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-
CC         phosphate + phosphate; Xref=Rhea:RHEA:11064, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:32966, ChEBI:CHEBI:43474, ChEBI:CHEBI:57634; EC=3.1.3.11;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01854}.
CC   -!- SIMILARITY: Belongs to the FBPase class 3 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01854}.
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DR   EMBL; CP000560; ABS76029.1; -; Genomic_DNA.
DR   RefSeq; WP_012118863.1; NC_009725.2.
DR   AlphaFoldDB; A7ZAK3; -.
DR   STRING; 326423.RBAM_037000; -.
DR   EnsemblBacteria; ABS76029; ABS76029; RBAM_037000.
DR   KEGG; bay:RBAM_037000; -.
DR   HOGENOM; CLU_028392_2_0_9; -.
DR   OMA; AKMHKAI; -.
DR   UniPathway; UPA00138; -.
DR   Proteomes; UP000001120; Chromosome.
DR   GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.60.21.10; -; 1.
DR   HAMAP; MF_01854; FBPase_class3; 1.
DR   InterPro; IPR009164; FBPtase_class3.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   Pfam; PF06874; FBPase_2; 1.
DR   PIRSF; PIRSF000906; FBPtase_Bacill; 1.
DR   SUPFAM; SSF56300; SSF56300; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Hydrolase; Manganese.
FT   CHAIN           1..641
FT                   /note="Fructose-1,6-bisphosphatase class 3"
FT                   /id="PRO_0000363072"
SQ   SEQUENCE   641 AA;  74558 MW;  DDBD8791D9C4FB4B CRC64;
     METKYLDLLA QKYDCEEKVV TEIINLKAIL NLPKGTEHFV SDLHGEYQAF QHVLRNGSGR
     VKEKIRDIFS GVIYDREIDE LAALVYYPED KLKLIKHDFD TKEALNEWYK ETIHRMIKLV
     SYCSSKYTRS KLRKALPAQF AYISEELLYK TEQAANKEQY YSEIIEQIIA LGQADKLITG
     LAYSTQRLVV DHLHVVGDIY DRGPQPDKIM EELINYHSVD IQWGNHDVLW IGAYSGSKVC
     LANIIRICAR YDNLDIIEDV YGINLRPLLN LAEKYYDDNP SFRPKADENR PEDEIKQITK
     IHQAIAMIQF KLESPIIKRR PNFNMEERLL LEKIDYDRNE ITLNGKTYQL ENTCFATVNP
     KQPDELLEEE AEVMDKLLFS VQNSEKLGRH MNFMMKKGSL YLKYNGNLLI HGCIPVDENG
     SMETMMIEDK AYAGRELLDV FERFLREAFA HPEETDDLAT DMTWYLWTGE YSSLFGKRAM
     TTFERYFIKE KETHKEKKNP YYYLREDEAA CRNILMEFGL NPDHGHIING HTPVKEIEGE
     DPIKANGKMI VIDGGFSKAY QSTTGIAGYT LLYNSYGMQL VAHKHFNSKA EVLSTGTDVL
     TVKRLVDKEL ERKKVKETNV GEELMKEVAI LEKLREYRYM K