ID   F16PC_FINM2             Reviewed;         650 AA.
AC   B0S0K3;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Fructose-1,6-bisphosphatase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE            Short=FBPase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE            EC=3.1.3.11 {ECO:0000255|HAMAP-Rule:MF_01854};
DE   AltName: Full=D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
GN   Name=fbp {ECO:0000255|HAMAP-Rule:MF_01854}; OrderedLocusNames=FMG_0509;
OS   Finegoldia magna (strain ATCC 29328 / DSM 20472 / WAL 2508)
OS   (Peptostreptococcus magnus).
OC   Bacteria; Firmicutes; Tissierellia; Tissierellales; Peptoniphilaceae;
OC   Finegoldia.
OX   NCBI_TaxID=334413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29328 / DSM 20472 / WAL 2508;
RX   PubMed=18263572; DOI=10.1093/dnares/dsm030;
RA   Goto T., Yamashita A., Hirakawa H., Matsutani M., Todo K., Ohshima K.,
RA   Toh H., Miyamoto K., Kuhara S., Hattori M., Shimizu T., Akimoto S.;
RT   "Complete genome sequence of Finegoldia magna, an anaerobic opportunistic
RT   pathogen.";
RL   DNA Res. 15:39-47(2008).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-
CC         phosphate + phosphate; Xref=Rhea:RHEA:11064, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:32966, ChEBI:CHEBI:43474, ChEBI:CHEBI:57634; EC=3.1.3.11;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01854}.
CC   -!- SIMILARITY: Belongs to the FBPase class 3 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01854}.
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DR   EMBL; AP008971; BAG07927.1; -; Genomic_DNA.
DR   RefSeq; WP_012290453.1; NC_010376.1.
DR   AlphaFoldDB; B0S0K3; -.
DR   STRING; 334413.FMG_0509; -.
DR   PRIDE; B0S0K3; -.
DR   EnsemblBacteria; BAG07927; BAG07927; FMG_0509.
DR   KEGG; fma:FMG_0509; -.
DR   eggNOG; COG3855; Bacteria.
DR   HOGENOM; CLU_028392_2_0_9; -.
DR   OMA; AKMHKAI; -.
DR   OrthoDB; 378029at2; -.
DR   UniPathway; UPA00138; -.
DR   Proteomes; UP000001319; Chromosome.
DR   GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.60.21.10; -; 1.
DR   HAMAP; MF_01854; FBPase_class3; 1.
DR   InterPro; IPR009164; FBPtase_class3.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   Pfam; PF06874; FBPase_2; 1.
DR   SUPFAM; SSF56300; SSF56300; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Hydrolase; Manganese; Reference proteome.
FT   CHAIN           1..650
FT                   /note="Fructose-1,6-bisphosphatase class 3"
FT                   /id="PRO_0000363092"
SQ   SEQUENCE   650 AA;  75232 MW;  5EE9ED310BE8FCE7 CRC64;
     MNNLKYLKLL AKEFPTIEQA ANKIISLTSL SVLPKGTEYF LSDLHGQYDS FNRIIKSASG
     NTRIKIDLEF KDKLSESRKN QLANLIYDPK TIINITKEND EYTETWIRDT IFYLIRIAKR
     VASKYSRQKV RNQTPFYYRD LIDEMLNIQY ESLNKKEYFN QLLDSIIKIE VSENFIITLC
     ELIQDLNIDW LHIVGDIFDR GKRPDIIMDT LIAKKDVDIQ YGNHDVTWIG AYLGSYVNAC
     NVVRNAISYN NFQSLEDGYG INLRLLSTLA DESYYDDPCE RFKVRILDDN KHSETDLLHA
     ARMHKAISII QFKLENQLFK RNPEFEQLDR LYLERIDFKN GIYKDANGKA HALLDIKFPT
     VDPDNPLELT PSEQEVVECI SKSFRTSHRL KEHMDFLFSY GSVYKIANSN LLFHGCIPMN
     KDGSFEEFTY QSNTYSGKSL LDFFEGIINS ARNMDDNDPD RQTALDFFWY MWCGPKSPMF
     GKSKISTFEN FFITDKDVRK EVSNPYFSLS KIEKYADKIF EEFNMNPETS HIINGHVPVK
     SINGEKPVSA NGKTYVIDGG ISEAYQKKTG IAGYTLTFNS HHLAIAKHKN FQVMESVHGA
     YTPEVTITEE FPKRMLIKDT DEGEEILELI EDLESLIDAY RSGTIQQNSN