ID   F16PC_LATSS             Reviewed;         641 AA.
AC   Q38UP9;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Fructose-1,6-bisphosphatase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE            Short=FBPase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE            EC=3.1.3.11 {ECO:0000255|HAMAP-Rule:MF_01854};
DE   AltName: Full=D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
GN   Name=fbp {ECO:0000255|HAMAP-Rule:MF_01854}; OrderedLocusNames=LCA_1778;
OS   Latilactobacillus sakei subsp. sakei (strain 23K) (Lactobacillus sakei
OS   subsp. sakei).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Latilactobacillus.
OX   NCBI_TaxID=314315;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=23K;
RX   PubMed=16273110; DOI=10.1038/nbt1160;
RA   Chaillou S., Champomier-Verges M.-C., Cornet M., Crutz-Le Coq A.-M.,
RA   Dudez A.-M., Martin V., Beaufils S., Darbon-Rongere E., Bossy R., Loux V.,
RA   Zagorec M.;
RT   "The complete genome sequence of the meat-borne lactic acid bacterium
RT   Lactobacillus sakei 23K.";
RL   Nat. Biotechnol. 23:1527-1533(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-
CC         phosphate + phosphate; Xref=Rhea:RHEA:11064, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:32966, ChEBI:CHEBI:43474, ChEBI:CHEBI:57634; EC=3.1.3.11;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01854}.
CC   -!- SIMILARITY: Belongs to the FBPase class 3 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01854}.
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DR   EMBL; CR936503; CAI56086.1; -; Genomic_DNA.
DR   RefSeq; WP_011375460.1; NC_007576.1.
DR   AlphaFoldDB; Q38UP9; -.
DR   STRING; 314315.LCA_1778; -.
DR   EnsemblBacteria; CAI56086; CAI56086; LCA_1778.
DR   KEGG; lsa:LCA_1778; -.
DR   eggNOG; COG3855; Bacteria.
DR   HOGENOM; CLU_028392_2_0_9; -.
DR   OMA; AKMHKAI; -.
DR   OrthoDB; 378029at2; -.
DR   BioCyc; LSAK314315:LCA_RS08840-MON; -.
DR   UniPathway; UPA00138; -.
DR   Proteomes; UP000002707; Chromosome.
DR   GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_01854; FBPase_class3; 1.
DR   InterPro; IPR009164; FBPtase_class3.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   Pfam; PF06874; FBPase_2; 1.
DR   PIRSF; PIRSF000906; FBPtase_Bacill; 1.
DR   SUPFAM; SSF56300; SSF56300; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Hydrolase; Manganese; Reference proteome.
FT   CHAIN           1..641
FT                   /note="Fructose-1,6-bisphosphatase class 3"
FT                   /id="PRO_0000363096"
SQ   SEQUENCE   641 AA;  73282 MW;  2CC4EF2C9DD36FE8 CRC64;
     MINNKMKTLS DKYPTKMAVT SEIINLKAIL NLPKPTEAFM SDLHGEYDAF QHLIRTGAGN
     LRQKINELFS GEMTPETMQA FAFLVYYPTE RLALKHKALS ENELNQWYLT TFKRMIDLLK
     FVSTKYTRSK VRKAMAPDFV YITEELMYGD VANVDKKRYF QEITATIIEL GQADALIIAT
     SHTIQRLVVD QWHIIGDIYD RGPHPDLIVD QLTQLPAVDV QWGNHDILWF GAASGSELCL
     LNLLRICARY NNLAIIEETY GIALTDLVRF AAQHYQANSA FMPVEDPNQG PLTHAEKLKI
     SQVQQALAIM QFKLELTVIK RHPEFNMDHR LLLSQVDFKR RILHLNGQEY PLKNTCFQLV
     DPENPEALTA EESQIIADLL AAFTRCQKLR KHLTFLIDHG SMYRIYNQNL LFHGCLPVDA
     QGHFLTLTLA NQNYAGKQLL DFFDQQIRSS FNHPLHQANL STDLLWYLWT GPLSPLFGKN
     AMTTFERYFC PDPETHVETK NAYYSLRHDA DFIQQLLSEF NLSPETGHIL NGHTPVKKGH
     DPIMANRQMI VIDGGFSKAY HHTTGIGGFT LLYNSYGMQL VTHQPFTTKA DAIANMKDII
     STRRVIDQVS QRQRVSQTNI GAAIKTEIEQ LQTLLTIQPD H