ID   F16PC_LISIN             Reviewed;         653 AA.
AC   Q92DI8;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Fructose-1,6-bisphosphatase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE            Short=FBPase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE            EC=3.1.3.11 {ECO:0000255|HAMAP-Rule:MF_01854};
DE   AltName: Full=D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
GN   Name=fbp {ECO:0000255|HAMAP-Rule:MF_01854}; OrderedLocusNames=lin0825;
OS   Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=272626;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-680 / CLIP 11262;
RX   PubMed=11679669; DOI=10.1126/science.1063447;
RA   Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA   Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA   Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA   Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA   Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA   Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA   Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA   Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA   Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA   Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT   "Comparative genomics of Listeria species.";
RL   Science 294:849-852(2001).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-
CC         phosphate + phosphate; Xref=Rhea:RHEA:11064, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:32966, ChEBI:CHEBI:43474, ChEBI:CHEBI:57634; EC=3.1.3.11;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01854}.
CC   -!- SIMILARITY: Belongs to the FBPase class 3 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01854}.
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DR   EMBL; AL596166; CAC96057.1; -; Genomic_DNA.
DR   PIR; AI1535; AI1535.
DR   RefSeq; WP_010990630.1; NC_003212.1.
DR   AlphaFoldDB; Q92DI8; -.
DR   STRING; 272626.lin0825; -.
DR   EnsemblBacteria; CAC96057; CAC96057; CAC96057.
DR   KEGG; lin:fbp; -.
DR   eggNOG; COG3855; Bacteria.
DR   HOGENOM; CLU_028392_2_0_9; -.
DR   OMA; AKMHKAI; -.
DR   OrthoDB; 378029at2; -.
DR   UniPathway; UPA00138; -.
DR   Proteomes; UP000002513; Chromosome.
DR   GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.60.21.10; -; 1.
DR   HAMAP; MF_01854; FBPase_class3; 1.
DR   InterPro; IPR009164; FBPtase_class3.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   Pfam; PF06874; FBPase_2; 1.
DR   PIRSF; PIRSF000906; FBPtase_Bacill; 1.
DR   SUPFAM; SSF56300; SSF56300; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Hydrolase; Manganese.
FT   CHAIN           1..653
FT                   /note="Fructose-1,6-bisphosphatase class 3"
FT                   /id="PRO_0000363100"
SQ   SEQUENCE   653 AA;  76069 MW;  AA1533131C7656D9 CRC64;
     MENIDMKYLH LLAKQYPTIA KTATEIINLE AIMNLPKGTE HFLSDVHGEY SAFEQVLRNG
     SGVVKRKIRD IFGDELDDAE INSLSTLIYY PEEKMDLIAE EMDDMHDWYR TTLFRLIELC
     QYVASKYTRS KVRKAMPEDF AYILEELLHE NYNEEDKKMY YEEILQHIIS LDRAAEFISA
     LSRLIQQLVV DHLHIVGDVY DRGPYPDKIM DTLMNYHSLD FQWGNHDILW MGAASGSRVC
     AANVIRISAR YLNLDILEDS YGISLRPLAL FADEIYKNDP CTYFQPKNED NLNYSKAEIT
     QIARMHKAIS IIQFKLEGEI INRRKEFDMN HRLLLQMIDY KKGTIHLKGK DYQLLDTHFP
     TIDPNDPYKL TKEEKELIEK ITASFKNCRR LQKHVQFLYS KGSMFLTYNG NLLYHGCIPL
     YEDGTFMEMK LRGENFSGRE LLEQFEILTR EAYVRKPGTK EKKYACDIVW YLWTGAVSSL
     FGKSEMTTFE RYFIAEKETH KEEKNPYYKL RNEETICKQI LEEFGLDGEC GHIINGHTPV
     KEGKGESPIK ANTKMLVIDG GFAKAYHKET TLAGYTLLYN SYGLQLVSHQ PFTTKEDAIK
     NETDILSTRQ VIEMEINRKR VRDTDIGKNL NEQATDLKML LEAYRNGSLH ENS