ID   F16PC_LISMC             Reviewed;         653 AA.
AC   C1L199;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Fructose-1,6-bisphosphatase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE            Short=FBPase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE            EC=3.1.3.11 {ECO:0000255|HAMAP-Rule:MF_01854};
DE   AltName: Full=D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
GN   Name=fbp {ECO:0000255|HAMAP-Rule:MF_01854}; OrderedLocusNames=Lm4b_00846;
OS   Listeria monocytogenes serotype 4b (strain CLIP80459).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=568819;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIP80459;
RX   PubMed=22530965; DOI=10.1186/1471-2164-13-144;
RA   Hain T., Ghai R., Billion A., Kuenne C.T., Steinweg C., Izar B.,
RA   Mohamed W., Mraheil M., Domann E., Schaffrath S., Karst U., Goesmann A.,
RA   Oehm S., Puhler A., Merkl R., Vorwerk S., Glaser P., Garrido P.,
RA   Rusniok C., Buchrieser C., Goebel W., Chakraborty T.;
RT   "Comparative genomics and transcriptomics of lineages I, II, and III
RT   strains of Listeria monocytogenes.";
RL   BMC Genomics 13:144-144(2012).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-
CC         phosphate + phosphate; Xref=Rhea:RHEA:11064, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:32966, ChEBI:CHEBI:43474, ChEBI:CHEBI:57634; EC=3.1.3.11;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01854}.
CC   -!- SIMILARITY: Belongs to the FBPase class 3 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01854}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FM242711; CAS04614.1; -; Genomic_DNA.
DR   RefSeq; WP_003740500.1; NC_012488.1.
DR   AlphaFoldDB; C1L199; -.
DR   KEGG; lmc:Lm4b_00846; -.
DR   HOGENOM; CLU_028392_2_0_9; -.
DR   OMA; AKMHKAI; -.
DR   BioCyc; LMON568819:LM4B_RS04205-MON; -.
DR   UniPathway; UPA00138; -.
DR   GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.60.21.10; -; 1.
DR   HAMAP; MF_01854; FBPase_class3; 1.
DR   InterPro; IPR009164; FBPtase_class3.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   Pfam; PF06874; FBPase_2; 1.
DR   PIRSF; PIRSF000906; FBPtase_Bacill; 1.
DR   SUPFAM; SSF56300; SSF56300; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Hydrolase; Manganese.
FT   CHAIN           1..653
FT                   /note="Fructose-1,6-bisphosphatase class 3"
FT                   /id="PRO_1000216146"
SQ   SEQUENCE   653 AA;  75575 MW;  0613624F7529BA43 CRC64;
     MKTIDMKYLR LLAKEYPTIA KTATEIINLE AIMNLPKGTE HFLSDVHGEY SAFEQVLRNG
     SGVVKRKIRD IFGAELDDAE INSLSTLIYY PEEKMDLLAS ETEDLQAWYR TTLFRLIELC
     QYVASKYTRS KVRKAMPEDF AYILEELLHE NYNEDDKKLY YEEILQHIIS LGRAEEFISA
     LSLLIQQLVV DHLHIVGDVY DRGPYPDKIM DTLMNYHSLD FQWGNHDILW MGAASGSRVC
     AANVIRISAR YLNLDILEDS YGISLRPLAL FADEVYKDDP CTYFQPKNEE NINYSNAEIT
     QIARMHKAIS IIQFKLEGEI INRRKEFDMD HRLLLQFIDY KKGTIHLKGK EYLLLDSHFP
     TINPEKPYEL TDAERELIGK ITAAFKNCRR LQKHVQFLYS KGSMFLTYNG NLLYHGCIPL
     HEDGTFMEMK LRGEKYAGRS LLEQFEILTR EAYVRPTGTK EKKYACDIVW YLWTGAISSL
     FGKSEMTTFE RYFVAEKETH TEEKNPYYKL RNNELICKQI LEEFGLDGEC GHIINGHTPV
     KEGKGESPIK ANGKMLVIDG GFAKAYHKET NLAGYTLLFN SYGLQLVSHQ PFTTKEDAIK
     NETDILSTRQ VIEMEINRKR VRDTDIGAKL SEQAEDLKLL LDAYRNGLLH ENR