ID   F16PC_LISMF             Reviewed;         653 AA.
AC   Q721Y7;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Fructose-1,6-bisphosphatase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE            Short=FBPase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE            EC=3.1.3.11 {ECO:0000255|HAMAP-Rule:MF_01854};
DE   AltName: Full=D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
GN   Name=fbp {ECO:0000255|HAMAP-Rule:MF_01854};
GN   OrderedLocusNames=LMOf2365_0847;
OS   Listeria monocytogenes serotype 4b (strain F2365).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=265669;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F2365;
RX   PubMed=15115801; DOI=10.1093/nar/gkh562;
RA   Nelson K.E., Fouts D.E., Mongodin E.F., Ravel J., DeBoy R.T., Kolonay J.F.,
RA   Rasko D.A., Angiuoli S.V., Gill S.R., Paulsen I.T., Peterson J.D.,
RA   White O., Nelson W.C., Nierman W.C., Beanan M.J., Brinkac L.M.,
RA   Daugherty S.C., Dodson R.J., Durkin A.S., Madupu R., Haft D.H.,
RA   Selengut J., Van Aken S.E., Khouri H.M., Fedorova N., Forberger H.A.,
RA   Tran B., Kathariou S., Wonderling L.D., Uhlich G.A., Bayles D.O.,
RA   Luchansky J.B., Fraser C.M.;
RT   "Whole genome comparisons of serotype 4b and 1/2a strains of the food-borne
RT   pathogen Listeria monocytogenes reveal new insights into the core genome
RT   components of this species.";
RL   Nucleic Acids Res. 32:2386-2395(2004).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-
CC         phosphate + phosphate; Xref=Rhea:RHEA:11064, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:32966, ChEBI:CHEBI:43474, ChEBI:CHEBI:57634; EC=3.1.3.11;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01854}.
CC   -!- SIMILARITY: Belongs to the FBPase class 3 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01854}.
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DR   EMBL; AE017262; AAT03627.1; -; Genomic_DNA.
DR   RefSeq; WP_003740500.1; NC_002973.6.
DR   AlphaFoldDB; Q721Y7; -.
DR   DNASU; 2797058; -.
DR   KEGG; lmf:LMOf2365_0847; -.
DR   HOGENOM; CLU_028392_2_0_9; -.
DR   OMA; AKMHKAI; -.
DR   UniPathway; UPA00138; -.
DR   GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.60.21.10; -; 1.
DR   HAMAP; MF_01854; FBPase_class3; 1.
DR   InterPro; IPR009164; FBPtase_class3.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   Pfam; PF06874; FBPase_2; 1.
DR   PIRSF; PIRSF000906; FBPtase_Bacill; 1.
DR   SUPFAM; SSF56300; SSF56300; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Hydrolase; Manganese.
FT   CHAIN           1..653
FT                   /note="Fructose-1,6-bisphosphatase class 3"
FT                   /id="PRO_0000363102"
SQ   SEQUENCE   653 AA;  75575 MW;  0613624F7529BA43 CRC64;
     MKTIDMKYLR LLAKEYPTIA KTATEIINLE AIMNLPKGTE HFLSDVHGEY SAFEQVLRNG
     SGVVKRKIRD IFGAELDDAE INSLSTLIYY PEEKMDLLAS ETEDLQAWYR TTLFRLIELC
     QYVASKYTRS KVRKAMPEDF AYILEELLHE NYNEDDKKLY YEEILQHIIS LGRAEEFISA
     LSLLIQQLVV DHLHIVGDVY DRGPYPDKIM DTLMNYHSLD FQWGNHDILW MGAASGSRVC
     AANVIRISAR YLNLDILEDS YGISLRPLAL FADEVYKDDP CTYFQPKNEE NINYSNAEIT
     QIARMHKAIS IIQFKLEGEI INRRKEFDMD HRLLLQFIDY KKGTIHLKGK EYLLLDSHFP
     TINPEKPYEL TDAERELIGK ITAAFKNCRR LQKHVQFLYS KGSMFLTYNG NLLYHGCIPL
     HEDGTFMEMK LRGEKYAGRS LLEQFEILTR EAYVRPTGTK EKKYACDIVW YLWTGAISSL
     FGKSEMTTFE RYFVAEKETH TEEKNPYYKL RNNELICKQI LEEFGLDGEC GHIINGHTPV
     KEGKGESPIK ANGKMLVIDG GFAKAYHKET NLAGYTLLFN SYGLQLVSHQ PFTTKEDAIK
     NETDILSTRQ VIEMEINRKR VRDTDIGAKL SEQAEDLKLL LDAYRNGLLH ENR