ID   F16PC_LISW6             Reviewed;         653 AA.
AC   A0AGV7;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   28-NOV-2006, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Fructose-1,6-bisphosphatase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE            Short=FBPase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE            EC=3.1.3.11 {ECO:0000255|HAMAP-Rule:MF_01854};
DE   AltName: Full=D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
GN   Name=fbp {ECO:0000255|HAMAP-Rule:MF_01854}; OrderedLocusNames=lwe0821;
OS   Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / CIP 8149 /
OS   NCTC 11857 / SLCC 5334 / V8).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=386043;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35897 / DSM 20650 / CIP 8149 / NCTC 11857 / SLCC 5334 / V8;
RX   PubMed=16936040; DOI=10.1128/jb.00758-06;
RA   Hain T., Steinweg C., Kuenne C.T., Billion A., Ghai R., Chatterjee S.S.,
RA   Domann E., Kaerst U., Goesmann A., Bekel T., Bartels D., Kaiser O.,
RA   Meyer F., Puehler A., Weisshaar B., Wehland J., Liang C., Dandekar T.,
RA   Lampidis R., Kreft J., Goebel W., Chakraborty T.;
RT   "Whole-genome sequence of Listeria welshimeri reveals common steps in
RT   genome reduction with Listeria innocua as compared to Listeria
RT   monocytogenes.";
RL   J. Bacteriol. 188:7405-7415(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-
CC         phosphate + phosphate; Xref=Rhea:RHEA:11064, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:32966, ChEBI:CHEBI:43474, ChEBI:CHEBI:57634; EC=3.1.3.11;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01854}.
CC   -!- SIMILARITY: Belongs to the FBPase class 3 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01854}.
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DR   EMBL; AM263198; CAK20239.1; -; Genomic_DNA.
DR   RefSeq; WP_011701658.1; NC_008555.1.
DR   AlphaFoldDB; A0AGV7; -.
DR   STRING; 386043.lwe0821; -.
DR   EnsemblBacteria; CAK20239; CAK20239; lwe0821.
DR   GeneID; 61188710; -.
DR   KEGG; lwe:lwe0821; -.
DR   eggNOG; COG3855; Bacteria.
DR   HOGENOM; CLU_028392_2_0_9; -.
DR   OMA; AKMHKAI; -.
DR   OrthoDB; 378029at2; -.
DR   UniPathway; UPA00138; -.
DR   Proteomes; UP000000779; Chromosome.
DR   GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.60.21.10; -; 1.
DR   HAMAP; MF_01854; FBPase_class3; 1.
DR   InterPro; IPR009164; FBPtase_class3.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   Pfam; PF06874; FBPase_2; 1.
DR   PIRSF; PIRSF000906; FBPtase_Bacill; 1.
DR   SUPFAM; SSF56300; SSF56300; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Hydrolase; Manganese.
FT   CHAIN           1..653
FT                   /note="Fructose-1,6-bisphosphatase class 3"
FT                   /id="PRO_0000363103"
SQ   SEQUENCE   653 AA;  75654 MW;  56FDD156FC8E0441 CRC64;
     METNDMKYLQ LLATEYPTIA KTATEIINLE AIMNLPKGTE HFLSDVHGEY SAFEQVLRNG
     SGVIKRKIRD IFGEELDDAE INSLSTLIYY PEEKMDLIAD EMDDIHAWYR TTLFRLIELC
     QYVASKYTRS KVRKAMPEDF AYILEELLQE NYNEDDKKMY YEEILQHIIS LDRAEEFISA
     LARLIQQLVV DHLHIVGDVY DRGPYPDKIM DTLMHYHSVD FQWGNHDILW MGAASGSRVC
     AANVIRISAR YLNLDILEDS YGISLRPLAL FADEMYKNDP CTYFQPKNED NIDYSKAEIT
     QIARMHKAIA IIQFKLEGEI INRRQEFDMN HRLLLDFIDY TNGTIHIKGK DYDLLDSHFP
     TIDPENPYKL TTAEQELIEK IMASFKNCRR LQKHVQFLYA KGSMFLTYNG NLLYHGCIPL
     HEDGTFMEMK LRGKKFAGKE LLEQFEILTR EAYVRPPGTK EKKYACDIVW YLWTGAVSSL
     FGKSEMTTFE RYFVADKETH VEEKNPYYNL RNDEKVCKQI LEEFGLDGDC GHIINGHTPV
     KEGKGESPIK ASGKMLVIDG GFAKAYHKKT NLAGYTLLFN SYGLQLVSHQ PFTSKEDAIK
     NETDILSTRQ VIEMEINRKR VRDTDIGKKL NEQAEDLKKL LSAYRNGLLH EGR