F16PC_SACD2
ID F16PC_SACD2 Reviewed; 582 AA.
AC Q21FJ6;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 18-APR-2006, sequence version 1.
DT 25-MAY-2022, entry version 73.
DE RecName: Full=Fructose-1,6-bisphosphatase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE Short=FBPase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE EC=3.1.3.11 {ECO:0000255|HAMAP-Rule:MF_01854};
DE AltName: Full=D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
GN Name=fbp {ECO:0000255|HAMAP-Rule:MF_01854}; OrderedLocusNames=Sde_3278;
OS Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Cellvibrionales;
OC Cellvibrionaceae; Saccharophagus.
OX NCBI_TaxID=203122;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2-40 / ATCC 43961 / DSM 17024;
RX PubMed=18516288; DOI=10.1371/journal.pgen.1000087;
RA Weiner R.M., Taylor L.E. II, Henrissat B., Hauser L., Land M.,
RA Coutinho P.M., Rancurel C., Saunders E.H., Longmire A.G., Zhang H.,
RA Bayer E.A., Gilbert H.J., Larimer F., Zhulin I.B., Ekborg N.A., Lamed R.,
RA Richardson P.M., Borovok I., Hutcheson S.;
RT "Complete genome sequence of the complex carbohydrate-degrading marine
RT bacterium, Saccharophagus degradans strain 2-40 T.";
RL PLoS Genet. 4:E1000087-E1000087(2008).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-
CC phosphate + phosphate; Xref=Rhea:RHEA:11064, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:32966, ChEBI:CHEBI:43474, ChEBI:CHEBI:57634; EC=3.1.3.11;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC {ECO:0000255|HAMAP-Rule:MF_01854}.
CC -!- SIMILARITY: Belongs to the FBPase class 3 family. {ECO:0000255|HAMAP-
CC Rule:MF_01854}.
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DR EMBL; CP000282; ABD82533.1; -; Genomic_DNA.
DR RefSeq; WP_011469749.1; NC_007912.1.
DR AlphaFoldDB; Q21FJ6; -.
DR STRING; 203122.Sde_3278; -.
DR PRIDE; Q21FJ6; -.
DR EnsemblBacteria; ABD82533; ABD82533; Sde_3278.
DR KEGG; sde:Sde_3278; -.
DR eggNOG; COG3855; Bacteria.
DR HOGENOM; CLU_028392_2_0_6; -.
DR OMA; AKMHKAI; -.
DR OrthoDB; 378029at2; -.
DR UniPathway; UPA00138; -.
DR Proteomes; UP000001947; Chromosome.
DR GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.60.21.10; -; 1.
DR HAMAP; MF_01854; FBPase_class3; 1.
DR InterPro; IPR009164; FBPtase_class3.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR Pfam; PF06874; FBPase_2; 1.
DR SUPFAM; SSF56300; SSF56300; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism; Hydrolase; Manganese; Reference proteome.
FT CHAIN 1..582
FT /note="Fructose-1,6-bisphosphatase class 3"
FT /id="PRO_0000363109"
SQ SEQUENCE 582 AA; 65585 MW; E9CE4E5FE0B87D6B CRC64;
MTSNALKVFI SDLHGELDVF DFLADRQFGI LHLLIRQQFS PELNETLCAA IEASAIRLCR
AANASQAQLD RTSAVSKEIL FTALFLMVVQ QKAEDESLTI AIRRWGWLST VHRALSGDAQ
LSCTPFSQLV EMLAQNIRTL SAQDFFALVQ AFAKALFKKL SPELNIVGDI YDRGQDAFAI
MERLRGLPNV AIQWGNHDVV WMGAASGNLA CITVAVRICL RYGTLDMLHR DYGINLSRLE
RFAAKAYGDD DCAQFTPKGD LNAEEKLRIA RMHKAISIIQ FKLEGKLIAR RPEYTMADRL
LLDKINIANS TVTVGDAVHP LLDSNFPTLD VEQPYRLSED ERKVAEDLKQ QFLASAKLTQ
HMDILFHRGG MQKKTGDWLL YHACVPVDEQ GEFQPFALAP ETTRGQSLFN FCELEMRRGY
LNRMVINDRN ESDIAWFLWC GPHSPLFGKA RMTTFERYFV ADKQTHKEGK NEYYNLRSNP
EFLARVATEL KCSSDQVRIV NGHVPVKYQS GERPVQANGK LFSIDGGFSM PYRSATGLAG
FVLLEALGQI VLYRVIPNDK RYALEVEYQQ ILKPKAASVP AA
