ID   F16PC_SORC5             Reviewed;         641 AA.
AC   A9FZA0;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Fructose-1,6-bisphosphatase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE            Short=FBPase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
DE            EC=3.1.3.11 {ECO:0000255|HAMAP-Rule:MF_01854};
DE   AltName: Full=D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 {ECO:0000255|HAMAP-Rule:MF_01854};
GN   Name=fbp {ECO:0000255|HAMAP-Rule:MF_01854}; OrderedLocusNames=sce8557;
OS   Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So
OS   ce56)).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales; Sorangiineae;
OC   Polyangiaceae; Sorangium.
OX   NCBI_TaxID=448385;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=So ce56;
RX   PubMed=17965706; DOI=10.1038/nbt1354;
RA   Schneiker S., Perlova O., Kaiser O., Gerth K., Alici A., Altmeyer M.O.,
RA   Bartels D., Bekel T., Beyer S., Bode E., Bode H.B., Bolten C.J.,
RA   Choudhuri J.V., Doss S., Elnakady Y.A., Frank B., Gaigalat L., Goesmann A.,
RA   Groeger C., Gross F., Jelsbak L., Jelsbak L., Kalinowski J., Kegler C.,
RA   Knauber T., Konietzny S., Kopp M., Krause L., Krug D., Linke B., Mahmud T.,
RA   Martinez-Arias R., McHardy A.C., Merai M., Meyer F., Mormann S.,
RA   Munoz-Dorado J., Perez J., Pradella S., Rachid S., Raddatz G., Rosenau F.,
RA   Rueckert C., Sasse F., Scharfe M., Schuster S.C., Suen G.,
RA   Treuner-Lange A., Velicer G.J., Vorholter F.-J., Weissman K.J., Welch R.D.,
RA   Wenzel S.C., Whitworth D.E., Wilhelm S., Wittmann C., Bloecker H.,
RA   Puehler A., Mueller R.;
RT   "Complete genome sequence of the myxobacterium Sorangium cellulosum.";
RL   Nat. Biotechnol. 25:1281-1289(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-
CC         phosphate + phosphate; Xref=Rhea:RHEA:11064, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:32966, ChEBI:CHEBI:43474, ChEBI:CHEBI:57634; EC=3.1.3.11;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01854};
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01854}.
CC   -!- SIMILARITY: Belongs to the FBPase class 3 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01854}.
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DR   EMBL; AM746676; CAN98727.1; -; Genomic_DNA.
DR   RefSeq; WP_012241166.1; NC_010162.1.
DR   AlphaFoldDB; A9FZA0; -.
DR   STRING; 448385.sce8557; -.
DR   EnsemblBacteria; CAN98727; CAN98727; sce8557.
DR   KEGG; scl:sce8557; -.
DR   eggNOG; COG3855; Bacteria.
DR   HOGENOM; CLU_028392_2_0_7; -.
DR   OMA; AKMHKAI; -.
DR   OrthoDB; 378029at2; -.
DR   BioCyc; SCEL448385:SCE_RS43835-MON; -.
DR   UniPathway; UPA00138; -.
DR   Proteomes; UP000002139; Chromosome.
DR   GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.60.21.10; -; 1.
DR   HAMAP; MF_01854; FBPase_class3; 1.
DR   InterPro; IPR009164; FBPtase_class3.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   Pfam; PF06874; FBPase_2; 1.
DR   SUPFAM; SSF56300; SSF56300; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Hydrolase; Manganese; Reference proteome.
FT   CHAIN           1..641
FT                   /note="Fructose-1,6-bisphosphatase class 3"
FT                   /id="PRO_0000363110"
SQ   SEQUENCE   641 AA;  72194 MW;  3E02279ACCC02C0D CRC64;
     MLDTRELPLL RALAGRYPTT EAALSEIGHL RAILSLPKGT VHVVSDVHGE HRKLKHIINN
     ASGSLRPLVE RVFGDRLTAA EERALLSAVY YPRERYARVA SHSEGARWAF LIWTLAREVE
     VIRALSLRYT LRQVEAAFPE DMRGLLRELV SARATLGEGG YLDALLDPFV QHGREIEILR
     ATARAIRNLT VFELVVAGDL GDRGPRLDKV IEYLMRQPRV RVVWGNHDVS WMGASLGQEA
     LIATVVRLSL RYGRLSQLEE GFGISVAPLD RLARTAYADD PAERFAVRGE GLRDALLMAR
     MQKAAAVLQF KLEGQLCRRR PEYALEHRCL LHRIDARAGT VAIDGEVFPL LDARFPTLDP
     GDPYALTPDE AACVALLKES FLRSPALSRQ MRWMVQQGTT WLRRDRALIF HGCVPVDGEG
     ELLPFVVDGE VRRGRALFDA LERTVRRAFR AGAQEDVDML WYLWTGPLSP MFGKDRMTTF
     ESYFVADERT HRETKNPYFH LIHDAAFCGR VCREFGVDEE RGLIVNGHVP VRVERGESPI
     KASRRAVTID GAFSEAYGDK GYTLVLEASG ARLAQHHHFT SVEQAVEAGE DIIPVISDVE
     VYEAERRVGD TEKGEEIERE IELLERLIEA YRDGALLEQP R