ID   F16_VAR67               Reviewed;         231 AA.
AC   P0DSU9; P33874;
DT   16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT   16-OCT-2019, sequence version 1.
DT   12-AUG-2020, entry version 5.
DE   RecName: Full=Protein F16;
GN   ORFNames=C20L, F16L;
OS   Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=587200;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8109158; DOI=10.1016/0168-1702(93)90093-3;
RA   Shchelkunov S.N., Blinov V.M., Resenchuk S.M., Totmenin A.V.,
RA   Sandakhchiev L.S.;
RT   "Analysis of the nucleotide sequence of a 43 kbp segment of the genome of
RT   variola virus India-1967 strain.";
RL   Virus Res. 30:239-258(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8384129; DOI=10.1016/0014-5793(93)80041-r;
RA   Shchelkunov S.N., Blinov V.M., Sandakhchiev L.S.;
RT   "Genes of variola and vaccinia viruses necessary to overcome the host
RT   protective mechanisms.";
RL   FEBS Lett. 319:80-83(1993).
CC   -!- SUBCELLULAR LOCATION: Host nucleus, host nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae F16 protein family.
CC       {ECO:0000305}.
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DR   EMBL; X69198; CAA48981.1; -; Genomic_DNA.
DR   PIR; B36841; B36841.
DR   RefSeq; NP_042084.1; NC_001611.1.
DR   GeneID; 1486577; -.
DR   KEGG; vg:1486577; -.
DR   Proteomes; UP000002060; Genome.
DR   GO; GO:0044196; C:host cell nucleolus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006798; Poxvirus_F16.
DR   Pfam; PF04708; Pox_F16; 1.
DR   PIRSF; PIRSF015792; VAC_F16L; 1.
PE   3: Inferred from homology;
KW   Host nucleus; Reference proteome.
FT   CHAIN           1..231
FT                   /note="Protein F16"
FT                   /id="PRO_0000099517"
SQ   SEQUENCE   231 AA;  26497 MW;  4C7D6B051DD59FB7 CRC64;
     MKVVIVTSVA SLLDASIQFQ KTACRHHCNY LSMQIVKEIE EFGTINEKNL EFATWKDVIQ
     NDEIDALVFY RVKQISISTG VLYESMMRNR TKPISMFFVR DCLAFDGDPP SFRMTSCNIN
     AYNRNKIKDL IILMNMKTCN KKIIGEFIID NFGSVNALLS IINSNVTWVT SVINNSNGRG
     INIRVSNNKM LTITSFRRFV NKLKMYKTTK CASQLDNLCT EINKMDIIDK K