ID   F16_VARV                Reviewed;         231 AA.
AC   P0DSV0; P33874;
DT   16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT   16-OCT-2019, sequence version 1.
DT   29-SEP-2021, entry version 10.
DE   RecName: Full=Protein F16;
GN   ORFNames=C20L, F16L;
OS   Variola virus.
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=10255;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Bangladesh-1975;
RX   PubMed=8264798; DOI=10.1038/366748a0;
RA   Massung R.F., Esposito J.J., Liu L.I., Qi J., Utterback T.R., Knight J.C.,
RA   Aubin L., Yuran T.E., Parsons J.M., Loparev V.N., Selivanov N.A.,
RA   Cavallaro K.F., Kerlavage A.R., Mahy B.W.J., Venter J.C.;
RT   "Potential virulence determinants in terminal regions of variola smallpox
RT   virus genome.";
RL   Nature 366:748-751(1993).
CC   -!- SUBCELLULAR LOCATION: Host nucleus, host nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae F16 protein family.
CC       {ECO:0000305}.
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DR   EMBL; L22579; AAA60788.1; -; Genomic_DNA.
DR   PIR; T28478; T28478.
DR   RefSeq; NP_042084.1; NC_001611.1.
DR   GeneID; 1486577; -.
DR   KEGG; vg:1486577; -.
DR   Proteomes; UP000119805; Genome.
DR   GO; GO:0044196; C:host cell nucleolus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006798; Poxvirus_F16.
DR   Pfam; PF04708; Pox_F16; 1.
DR   PIRSF; PIRSF015792; VAC_F16L; 1.
PE   3: Inferred from homology;
KW   Host nucleus.
FT   CHAIN           1..231
FT                   /note="Protein F16"
FT                   /id="PRO_0000448189"
SQ   SEQUENCE   231 AA;  26497 MW;  4C7D6B051DD59FB7 CRC64;
     MKVVIVTSVA SLLDASIQFQ KTACRHHCNY LSMQIVKEIE EFGTINEKNL EFATWKDVIQ
     NDEIDALVFY RVKQISISTG VLYESMMRNR TKPISMFFVR DCLAFDGDPP SFRMTSCNIN
     AYNRNKIKDL IILMNMKTCN KKIIGEFIID NFGSVNALLS IINSNVTWVT SVINNSNGRG
     INIRVSNNKM LTITSFRRFV NKLKMYKTTK CASQLDNLCT EINKMDIIDK K