ID   F174A_RAT               Reviewed;         190 AA.
AC   Q5FVQ7;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Membrane protein FAM174A;
DE   AltName: Full=Transmembrane protein 157;
DE   Flags: Precursor;
GN   Name=Fam174a; Synonyms=Tmem157;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Liver;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FAM174 family. {ECO:0000305}.
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DR   EMBL; BC089835; AAH89835.1; -; mRNA.
DR   RefSeq; NP_001012350.1; NM_001012350.1.
DR   RefSeq; XP_006245641.1; XM_006245579.3.
DR   AlphaFoldDB; Q5FVQ7; -.
DR   SMR; Q5FVQ7; -.
DR   STRING; 10116.ENSRNOP00000046794; -.
DR   GlyGen; Q5FVQ7; 2 sites.
DR   PaxDb; Q5FVQ7; -.
DR   Ensembl; ENSRNOT00000050494; ENSRNOP00000046794; ENSRNOG00000019087.
DR   Ensembl; ENSRNOT00000080129; ENSRNOP00000073621; ENSRNOG00000019087.
DR   GeneID; 301634; -.
DR   KEGG; rno:301634; -.
DR   CTD; 345757; -.
DR   RGD; 1309973; Fam174a.
DR   eggNOG; ENOG502S4HB; Eukaryota.
DR   GeneTree; ENSGT00730000111385; -.
DR   InParanoid; Q5FVQ7; -.
DR   OrthoDB; 1507319at2759; -.
DR   PhylomeDB; Q5FVQ7; -.
DR   TreeFam; TF105425; -.
DR   PRO; PR:Q5FVQ7; -.
DR   Proteomes; UP000002494; Chromosome 9.
DR   Bgee; ENSRNOG00000019087; Expressed in quadriceps femoris and 20 other tissues.
DR   ExpressionAtlas; Q5FVQ7; baseline and differential.
DR   Genevisible; Q5FVQ7; RN.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR009565; DUF1180.
DR   PANTHER; PTHR28607; PTHR28607; 1.
DR   Pfam; PF06679; DUF1180; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..190
FT                   /note="Membrane protein FAM174A"
FT                   /id="PRO_0000263652"
FT   TOPO_DOM        30..123
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        124..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        145..190
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          37..119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          168..190
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        27
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        83
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   190 AA;  20228 MW;  FCF932CE9D24BA07 CRC64;
     MPTRRGCSGP CHFLASAFVL LLLPALNQSV VLPSTVPRAV QESKPLEPGP RTLSPLPPGP
     TAAQPRGQAQ SEGAGPRGAE SRNGSIPGAA SEADGPEGKA GESSLGGSLA VSPNPSDKPM
     TQRALTVLVV VSAAVLVYFV VRTVRMRRRN RKTRRYGVLD TNIENMELTP LEQDDEDDDN
     TLFDANHPRR