ID   F174B_BOVIN             Reviewed;         159 AA.
AC   Q1RMK9;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=Membrane protein FAM174B;
DE   Flags: Precursor;
GN   Name=FAM174B;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential for Golgi structural integrity.
CC       {ECO:0000250|UniProtKB:Q3ZCQ3}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q3ZCQ3};
CC       Single-pass type I membrane protein {ECO:0000255}. Golgi apparatus
CC       {ECO:0000250|UniProtKB:Q3ZCQ3}.
CC   -!- SIMILARITY: Belongs to the FAM174 family. {ECO:0000305}.
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DR   EMBL; BC114840; AAI14841.1; -; mRNA.
DR   RefSeq; NP_001069818.1; NM_001076350.1.
DR   AlphaFoldDB; Q1RMK9; -.
DR   SMR; Q1RMK9; -.
DR   STRING; 9913.ENSBTAP00000031187; -.
DR   PaxDb; Q1RMK9; -.
DR   PRIDE; Q1RMK9; -.
DR   GeneID; 614841; -.
DR   KEGG; bta:614841; -.
DR   CTD; 400451; -.
DR   eggNOG; ENOG502S4RE; Eukaryota.
DR   InParanoid; Q1RMK9; -.
DR   OrthoDB; 1612806at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; ISS:UniProtKB.
DR   InterPro; IPR009565; DUF1180.
DR   PANTHER; PTHR28607; PTHR28607; 1.
DR   Pfam; PF06679; DUF1180; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Glycoprotein; Golgi apparatus; Membrane; Reference proteome;
KW   Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..159
FT                   /note="Membrane protein FAM174B"
FT                   /id="PRO_0000326113"
FT   TOPO_DOM        28..90
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        112..159
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          28..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        39..53
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        54
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   159 AA;  16654 MW;  5715553B63E03859 CRC64;
     MRAALPPARL LPLLLLLALL GAPAARASRA QSAAPPQPGA ERQPRPPPGP GPGNATGTGS
     GEAAGGGGSS NSSGDALVTR ISSLLRDLHT LKAAVIVACA FTAFLIACLL LRVFRSGKRL
     KKTRKYDIIT TPAERVEMAP LNEEDDEDED STVFDIKYR