ID   F182B_HUMAN             Reviewed;         152 AA.
AC   Q5T319; Q4G0Q1;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Protein FAM182B;
GN   Name=FAM182B;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RX   PubMed=17974005; DOI=10.1186/1471-2164-8-399;
RA   Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,
RA   Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D.,
RA   Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A.,
RA   Wiemann S., Schupp I.;
RT   "The full-ORF clone resource of the German cDNA consortium.";
RL   BMC Genomics 8:399-399(2007).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11780052; DOI=10.1038/414865a;
RA   Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R.,
RA   Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L.,
RA   Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P.,
RA   Bird C.P., Blakey S.E., Bridgeman A.M., Brown A.J., Buck D., Burrill W.D.,
RA   Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G.,
RA   Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E.,
RA   Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D.,
RA   Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P.,
RA   Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E.,
RA   Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J.,
RA   Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D.,
RA   Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S.,
RA   Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D.,
RA   Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A.,
RA   Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T.,
RA   Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I.,
RA   Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M.,
RA   Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D.,
RA   Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M.,
RA   Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A.,
RA   Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L.,
RA   Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L.,
RA   Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.;
RT   "The DNA sequence and comparative analysis of human chromosome 20.";
RL   Nature 414:865-871(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q5T319-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q5T319-2; Sequence=VSP_034850, VSP_034851;
CC   -!- MISCELLANEOUS: [Isoform 2]: May be produced at very low levels due to a
CC       premature stop codon in the mRNA, leading to nonsense-mediated mRNA
CC       decay. {ECO:0000305}.
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DR   EMBL; AL096727; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; AL390198; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC042812; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; Q5T319; -.
DR   STRING; 9606.ENSP00000365585; -.
DR   BioMuta; FAM182B; -.
DR   DMDM; 74744694; -.
DR   PaxDb; Q5T319; -.
DR   PRIDE; Q5T319; -.
DR   UCSC; uc002wve.4; human. [Q5T319-1]
DR   GeneCards; FAM182B; -.
DR   HGNC; HGNC:34503; FAM182B.
DR   neXtProt; NX_Q5T319; -.
DR   eggNOG; ENOG502QYG6; Eukaryota.
DR   HOGENOM; CLU_1735628_0_0_1; -.
DR   InParanoid; Q5T319; -.
DR   PhylomeDB; Q5T319; -.
DR   TreeFam; TF340911; -.
DR   PathwayCommons; Q5T319; -.
DR   ChiTaRS; FAM182B; human.
DR   Pharos; Q5T319; Tdark.
DR   PRO; PR:Q5T319; -.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q5T319; protein.
DR   Genevisible; Q5T319; HS.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Reference proteome.
FT   CHAIN           1..152
FT                   /note="Protein FAM182B"
FT                   /id="PRO_0000344534"
FT   REGION          120..152
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         71..80
FT                   /note="VSATSSIAVY -> NRNAYSCGPL (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:15489334"
FT                   /id="VSP_034850"
FT   VAR_SEQ         81..152
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:15489334"
FT                   /id="VSP_034851"
SQ   SEQUENCE   152 AA;  15775 MW;  31706E9CABE2B1BB CRC64;
     MQEMVRELWM WNVEEEEHEV GICTWGGQHC GCPAKSLPGP HPGGVSAPQS ASQLMVKLLV
     WQKSVHKLRK VSATSSIAVY PCPGQSSGGA ESPAPGPGLA GWSHLCGAAL AEVQAAPVSQ
     AAVSDASLGP EWSQEGCRPG LTSGQHGGRD GR