F183A_HUMAN
ID F183A_HUMAN Reviewed; 134 AA.
AC A6NL82; B7ZBL8;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-JUN-2008, sequence version 2.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=Protein FAM183A;
GN Name=FAM183A;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16710414; DOI=10.1038/nature04727;
RA Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A.,
RA Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C.,
RA Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.,
RA Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C.,
RA Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W.,
RA Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J.,
RA Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J.,
RA Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y.,
RA Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J.,
RA Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S.,
RA Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K.,
RA Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R.,
RA Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M.,
RA Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S.,
RA Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J.,
RA Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W.,
RA McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N.,
RA Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V.,
RA Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J.,
RA Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E.,
RA Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S.,
RA Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M.,
RA White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H.,
RA Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E.,
RA Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G.,
RA Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.;
RT "The DNA sequence and biological annotation of human chromosome 1.";
RL Nature 441:315-321(2006).
CC -!- SIMILARITY: Belongs to the FAM183 family. {ECO:0000305}.
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DR EMBL; AL139138; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS44126.1; -.
DR RefSeq; NP_001094846.2; NM_001101376.2.
DR AlphaFoldDB; A6NL82; -.
DR STRING; 9606.ENSP00000334415; -.
DR BioMuta; FAM183A; -.
DR MassIVE; A6NL82; -.
DR PaxDb; A6NL82; -.
DR PeptideAtlas; A6NL82; -.
DR PRIDE; A6NL82; -.
DR Antibodypedia; 77971; 6 antibodies from 3 providers.
DR DNASU; 440585; -.
DR Ensembl; ENST00000335282.5; ENSP00000334415.3; ENSG00000186973.11.
DR GeneID; 440585; -.
DR KEGG; hsa:440585; -.
DR MANE-Select; ENST00000335282.5; ENSP00000334415.3; NM_001101376.3; NP_001094846.2.
DR UCSC; uc009vwo.4; human.
DR CTD; 440585; -.
DR DisGeNET; 440585; -.
DR GeneCards; FAM183A; -.
DR HGNC; HGNC:34347; FAM183A.
DR HPA; ENSG00000186973; Tissue enriched (fallopian).
DR neXtProt; NX_A6NL82; -.
DR OpenTargets; ENSG00000186973; -.
DR PharmGKB; PA164719746; -.
DR VEuPathDB; HostDB:ENSG00000186973; -.
DR eggNOG; ENOG502RZSS; Eukaryota.
DR GeneTree; ENSGT00390000006224; -.
DR InParanoid; A6NL82; -.
DR OMA; SQEIGWM; -.
DR OrthoDB; 1544712at2759; -.
DR PhylomeDB; A6NL82; -.
DR TreeFam; TF329423; -.
DR PathwayCommons; A6NL82; -.
DR BioGRID-ORCS; 440585; 21 hits in 1065 CRISPR screens.
DR ChiTaRS; FAM183A; human.
DR GenomeRNAi; 440585; -.
DR Pharos; A6NL82; Tdark.
DR PRO; PR:A6NL82; -.
DR Proteomes; UP000005640; Chromosome 1.
DR RNAct; A6NL82; protein.
DR Bgee; ENSG00000186973; Expressed in right uterine tube and 85 other tissues.
DR ExpressionAtlas; A6NL82; baseline and differential.
DR GO; GO:0097546; C:ciliary base; IBA:GO_Central.
DR InterPro; IPR029214; FAM183.
DR PANTHER; PTHR33865; PTHR33865; 1.
DR Pfam; PF14886; FAM183; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..134
FT /note="Protein FAM183A"
FT /id="PRO_0000340271"
FT REGION 76..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 134 AA; 15996 MW; 0BE58329A318251B CRC64;
MAGHPKEKVI PDEVHQNQIL RELYLKELRT QKLYTQYHVN PLRKIHTVTR KPMSWHDNLE
EPADARFLNL IHHAAQGPRK KYPETQTENQ EVGWDLEPLI NPERHDRRLN HFRVCSDITL
YKAKTWGLGD DHHK