ID   F187B_MACFA             Reviewed;         369 AA.
AC   Q4R7Z5;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Protein FAM187B;
DE   AltName: Full=Transmembrane protein 162;
DE   Flags: Precursor;
GN   Name=FAM187B; Synonyms=TMEM162; ORFNames=QtsA-14008;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FAM187 family. {ECO:0000305}.
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DR   EMBL; AB168666; BAE00777.1; -; mRNA.
DR   RefSeq; NP_001271482.1; NM_001284553.1.
DR   AlphaFoldDB; Q4R7Z5; -.
DR   STRING; 9541.XP_005588892.1; -.
DR   Ensembl; ENSMFAT00000010209; ENSMFAP00000035968; ENSMFAG00000034358.
DR   GeneID; 102128403; -.
DR   CTD; 148109; -.
DR   VEuPathDB; HostDB:ENSMFAG00000034358; -.
DR   eggNOG; ENOG502S0YJ; Eukaryota.
DR   GeneTree; ENSGT00530000063991; -.
DR   OMA; EACHVQC; -.
DR   OrthoDB; 1290951at2759; -.
DR   Proteomes; UP000233100; Chromosome 19.
DR   Bgee; ENSMFAG00000034358; Expressed in lymph node and 1 other tissue.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR039311; FAM187A/B.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR32178; PTHR32178; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..369
FT                   /note="Protein FAM187B"
FT                   /id="PRO_0000284627"
FT   TOPO_DOM        18..333
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        334..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        355..369
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        45
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        68
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        130
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   369 AA;  42377 MW;  5B5666E3DB01D6E4 CRC64;
     MPPMLWLLLN FAAPALGFYF SISCPSGKQC QQALLSGNDI LLYCNSSGAH WYYLFTQGKK
     GRLASLTNIS NMEIMPEGSL LIKDPSPSQT GLYHCWNKNG RQVVQYEIDF QDISTLHVTH
     KDLGQRPLQN ETLPLGSKEL IFTRWEPWQD CNRCKEPGER KRLGYCYIEE PLKEAMPCWL
     YLGEMLVWSS RLRPELQVEA CHVRCTNNTQ LRVDYVIFDN FRLDEETEFV WLDCPLGSMY
     RPVYWHANDT PLTWESQLSG RDFTTFLDPS TGGRQLQVFQ PAIYKCFVQQ ELVAQFNPAT
     SPETLEAQWR ENDAQWREAR KALPGRADSV LKGLKLVLLV GTVLVLLGAL LKFIRPSPGK
     RSKQVLMVK