ID   F193A_MOUSE             Reviewed;        1231 AA.
AC   Q8CGI1; Q499G1;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 2.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Protein FAM193A;
GN   Name=Fam193a;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J, and FVB/N-3; TISSUE=Eye, and Mammary tumor;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-293, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Brain, Brown adipose tissue, Kidney, Lung, Pancreas, and Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- SIMILARITY: Belongs to the FAM193 family. {ECO:0000305}.
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DR   EMBL; BC037112; AAH37112.1; -; mRNA.
DR   EMBL; BC099925; AAH99925.1; -; mRNA.
DR   RefSeq; NP_001230052.1; NM_001243123.1.
DR   AlphaFoldDB; Q8CGI1; -.
DR   SMR; Q8CGI1; -.
DR   BioGRID; 231087; 4.
DR   IntAct; Q8CGI1; 1.
DR   MINT; Q8CGI1; -.
DR   STRING; 10090.ENSMUSP00000138082; -.
DR   iPTMnet; Q8CGI1; -.
DR   PhosphoSitePlus; Q8CGI1; -.
DR   EPD; Q8CGI1; -.
DR   jPOST; Q8CGI1; -.
DR   MaxQB; Q8CGI1; -.
DR   PaxDb; Q8CGI1; -.
DR   PeptideAtlas; Q8CGI1; -.
DR   PRIDE; Q8CGI1; -.
DR   ProteomicsDB; 277016; -.
DR   Antibodypedia; 50867; 22 antibodies from 9 providers.
DR   Ensembl; ENSMUST00000094867; ENSMUSP00000092463; ENSMUSG00000037210.
DR   GeneID; 231128; -.
DR   KEGG; mmu:231128; -.
DR   CTD; 8603; -.
DR   MGI; MGI:2447768; Fam193a.
DR   VEuPathDB; HostDB:ENSMUSG00000037210; -.
DR   eggNOG; ENOG502QVAZ; Eukaryota.
DR   GeneTree; ENSGT00390000000973; -.
DR   InParanoid; Q8CGI1; -.
DR   OrthoDB; 171147at2759; -.
DR   PhylomeDB; Q8CGI1; -.
DR   TreeFam; TF330223; -.
DR   BioGRID-ORCS; 231128; 1 hit in 33 CRISPR screens.
DR   ChiTaRS; Fam193a; mouse.
DR   PRO; PR:Q8CGI1; -.
DR   Proteomes; UP000000589; Chromosome 5.
DR   RNAct; Q8CGI1; protein.
DR   Bgee; ENSMUSG00000037210; Expressed in animal zygote and 218 other tissues.
DR   ExpressionAtlas; Q8CGI1; baseline and differential.
DR   Genevisible; Q8CGI1; MM.
DR   InterPro; IPR029717; FAM193.
DR   InterPro; IPR031802; FAM193_C.
DR   InterPro; IPR029719; FAM193A.
DR   PANTHER; PTHR15109; PTHR15109; 1.
DR   PANTHER; PTHR15109:SF2; PTHR15109:SF2; 1.
DR   Pfam; PF15914; FAM193_C; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Phosphoprotein; Reference proteome.
FT   CHAIN           1..1231
FT                   /note="Protein FAM193A"
FT                   /id="PRO_0000089431"
FT   REGION          249..272
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          331..405
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          633..703
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          719..789
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          826..845
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          860..1174
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          106..142
FT                   /evidence="ECO:0000255"
FT   COILED          877..973
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        256..272
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        382..405
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        775..789
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        883..907
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        962..986
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1015..1029
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1039..1055
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1056..1070
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1097..1128
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1131..1149
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         293
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:21183079"
FT   MOD_RES         648
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P78312"
FT   MOD_RES         1136
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P78312"
FT   MOD_RES         1151
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P78312"
SQ   SEQUENCE   1231 AA;  136714 MW;  451534B775BE862E CRC64;
     MKVRLLRQLS AAAKAKAPSG LQGPPQAHHF VSLLLEEYAA LCQAARSIST FLGTLENEHL
     KKFQVTWELH NKHLFENLVF SEPLLQSNLP ALVSQIRLGT TTHDTCTEDM YSTLLQRYQR
     SEEELRKVAE EWLECQKRID AYVDEQMTMK TKQRMLTEDW EIFKQRRLIE EQLTNKKVVT
     GENNFTDTRR HMLSSRLSMP DCPNCNYRRR CACDDCSLSH ILTCGIMDTP VTDDIHIHQL
     PLQVDSAPDY LSEMRPPSVS SASSGSGSSS PITIQQHPRL ILTDNGSAPT FCSDDEDVAP
     LSAKFADIYP LTNYDDTNVV ANMNGIHSEL NGGGENMALK DESPQVSSTS RSSSEADDED
     ADGESSGEPP GAPKQEEAIG NGNPKTEESN VNTPPPSYPA QQAEQTPNTC ECHVCKQEAS
     GLPASAMTAG ALPPGHQFLS PEKPTHPALH LYPHIHGHVP LHTVPHLPRP LIHPTLYPAP
     PFTHSKALPP APVQSHTNKP QAFNASLQDH IYPSCFGNTP DWNSSKFISL WESEMMNDKN
     WNPGTFLPDT ISGNDILGPV LSETRPEALP PPPSNEAPAV SDIKEKKNAA KKKCLYNFQD
     AFMEANEVAM ANTVAMATSS ATSSVSCTAT TVQSSSSQFK VSSRRPPSIG DVFHGLNKED
     HRHSAPAAPR NSPTGLAPLP ALSPSALSPA STPHLPNLAA PSFPKTATTA PGFVDTRKSF
     CPTPVAPPPS TTDGSISAPP SVCSDPDCEG HRCENGVYDP QQDDGDESAD EDSCSEHSSS
     TSTSTNQKEG KYCDCCYCEF FGHGGPPAAP TSRNYAEMRE KLRLRLTKRK EEQPKKMEQI
     SEREGVVDHR RVEDLLQFIN SSEAKPVSSS RAAKRARHKQ RKLEEKARLE AEARAREHLH
     HQEEQKQREE EEDEEEEDEE QHFKEEFQRL QELQKLRAAK KKKKDRPSKD CSKLDMLARN
     FQAATESISN SENIHNGSLE QTEEPETSSH SPSRHMNHSE PRPGPGANGD ATDPVDPRDP
     SKLLLPKEVN GKQHEPLAFL LDMMHHHKEG NSKQKLKQTS KTSNEPARKP TEPPKTTEVQ
     LKPRAQPELK PKVVDLALLT EQKREERKTN SNNNNKKQLS HIKEEKLSTV TPEPPSPSQL
     LQNGRLILAS SPQPKGKNKK NKKKKGDRTS SSLDDVFLPK DIDLDSVDMD ETEREVEYFK
     RFCLDSARQN RQRLSINWSN FSLKKATFAA H